FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term X-linked lissencephaly 2 ID (Ontology) DOID:0112238 (Human Disease)
Definition A lissencephaly characterized by structural brain anomalies, early-onset intractable seizures, severe psychomotor retardation, and ambiguous genitalia that has_material_basis_in mutation in ARX on chromosome Xp21.3.
Also Known As "X-linked lissencephaly with abnormal genitalia" ; "X-linked lissencephaly with ambiguous genitalia" ; "X-linked lissencephaly-corpus callosum agenesis-genital anomalies syndrome" (for all, see Synonyms field below)
Comment
Links to External Ontologies
DO.org
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 X-linked lissencephaly 2       3
 for disease ribbon | X-linked lissencephaly 2       3
 model of | X-linked lissencephaly 2       3
Spanning Tree (Parents/Children)
Only view relationship: 
monogenic disease
 |__X-linked monogenic disease_________
congenital nervous system abnormality  |
 |__lissencephaly______________________|
                                       X-linked lissencephaly 2  3 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a lissencephaly
X-linked monogenic disease
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "X-linked lissencephaly with abnormal genitalia" EXACT
    "X-linked lissencephaly with ambiguous genitalia" EXACT
    "X-linked lissencephaly-corpus callosum agenesis-genital anomalies syndrome" EXACT
    "XLAG" EXACT OMO:0003012
    "XLAG (X-linked lissencephaly with abnormal genitalia) syndrome" EXACT
    "XLIS2" EXACT OMO:0003012
Secondary IDs
hide External Crossreferences & Linkouts
MIM:300215
ORDO:452