FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term buphthalmos ID (Ontology) DOID:11211 (Human Disease)
Definition A hydrophthalmos characterized by early onset glaucoma in one or both eyes with elevated intraocular pressure, increased corneal diameter, and swelling of the globe and has_symptom early vision loss, photophobia, blepharospasm, tearing, increased corneal diameter, increased corneal thickness, and enlarged globe. Buphthalmos is caused by severe congenital defects of the trabecular meshwork and anterior chamber angle that block aqueous outflow and raises intraocular pressure, leading to optic nerve atrophy and early vision loss.
Also Known As "primary congenital glaucoma 3A" ; "simple buphthalmos"
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 buphthalmos       2
 for disease ribbon | buphthalmos       2
 model of | buphthalmos       2
Spanning Tree (Parents/Children)
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  primary congenital glaucoma
   |__hydrophthalmos
       |__buphthalmos  2 rec.
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Synonyms
  • "primary congenital glaucoma 3A" EXACT
    "simple buphthalmos" EXACT
Secondary IDs
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ICD9CM:743.21
MIM:231300
SNOMEDCT_US_2023_03_01:204116009
UMLS_CUI:C0311251