FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term common variable immunodeficiency ID (Ontology) DOID:12177 (Human Disease)
Definition An agammaglobulinemia that is characterized by low Ig levels with phenotypically normal B cells that can proliferate but do not develop into Ig-producing cells and that esults in insufficient production of antibodies needed to respond to exposure of pathogens.
Also Known As "acquired agammaglobulinemia" ; "acquired hypogammaglobulinemia" ; "common variable agammaglobulinemia" (for all, see Synonyms field below)
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autosomal genetic disease
 |__autosomal recessive disease__
B cell deficiency                |
 |__agammaglobulinemia___________|
                                 common variable immunodeficiency  9 rec.
                                  |__common variable immunodeficiency 1
                                  |__common variable immunodeficiency 2
                                  |__common variable immunodeficiency 3
                                  |__common variable immunodeficiency 4
                                  |__common variable immunodeficiency 5
                                  |__common variable immunodeficiency 6 4 rec.
                                  |__common variable immunodeficiency 7 1 rec.
                                  |__common variable immunodeficiency 8 1 rec.
                                  |__common variable immunodeficiency 10 1 rec.
                                  |__common variable immunodeficiency 11
                                  |__common variable immunodeficiency 12 1 rec.
                                  |__common variable immunodeficiency 13 1 rec.
                                  |__common variable immunodeficiency 14 1 rec.
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Is a autosomal recessive disease
agammaglobulinemia
Part of
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Synonyms
  • "acquired agammaglobulinemia" EXACT
    "acquired hypogammaglobulinemia" EXACT
    "common variable agammaglobulinemia" EXACT
    "CVID" EXACT OMO:0003012
    "sporadic hypogammaglobulinemia" EXACT
Secondary IDs
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GARD:6140
ICD10CM:D83
ICD9CM:279.06
MESH:D017074
MIM:PS607594
ORDO:1572
SNOMEDCT_US_2023_03_01:191010004
UMLS_CUI:C0009447