FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term cerebral degeneration ID (Ontology) DOID:1443 (Human Disease)
Definition A brain disease that is characterized by loss of structure or function of neurons, including death of neurons and loss of brain tissue.
Also Known As "Brain degeneration"
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DO.org
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Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Human Disease Models (FBhh)  DOID       1
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 Genes Human Disease Models
 cerebral degeneration       1      1
Spanning Tree (Parents/Children)
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  central nervous system disease
   |__brain disease
       |__cerebral degeneration  111 rec.
           |__cerebral lipidosis
           |__hydrocephalus 6 rec.
           |   |__communicating hydrocephalus(+) 1 rec.
           |   |__obstructive hydrocephalus
           |__leukodystrophy 103 rec.
           |   |__adrenoleukodystrophy 11 rec.
           |   |__adult onset demyelinating leukodystrophy(+) 2 rec.
           |   |__adult-onset leukoencephalopathy with axonal spheroids and pigmented glia 1 rec.
           |   |__Alexander disease 39 rec.
           |   |__CADASIL(+) 2 rec.
           |   |__Canavan disease
           |   |__hypomyelinating leukodystrophy(+) 40 rec.
           |   |__leukoencephalopathy with vanishing white matter(+) 5 rec.
           |   |__megalencephalic leukoencephalopathy with subcortical cysts(+)
           |   |__progressive leukoencephalopathy with ovarian failure 2 rec.
           |   |__RNASET2-deficient cystic leukoencephalopathy 1 rec.
           |__neuroaxonal dystrophy
           |   |__CSF1R-related brain malformation and osteopetrosis
           |__senile degeneration of brain
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Synonyms
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Secondary IDs
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GARD:6019
ICD9CM:331.9
SNOMEDCT_US_2023_03_01:52522001
UMLS_CUI:C0154671