FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term Langerhans-cell histiocytosis ID (Ontology) DOID:2571 (Human Disease)
Definition A histiocytosis that is characterized by clonal proliferation of Langerhans cells.
Also Known As "Histiocytosis X" ; "Langerhan's cell histiocytosis" ; "Langerhans cell granulomatosis" (for all, see Synonyms field below)
Comment
Links to External Ontologies
DO.org
Annotations
Records annotated with this term OR any of its CHILD TERMS
No relevant records available
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available
Spanning Tree (Parents/Children)
Only view relationship: 
  lymphatic system disease
   |__histiocytosis
       |__Langerhans-cell histiocytosis
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a histiocytosis
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "Histiocytosis X" EXACT
    "Langerhan's cell histiocytosis" EXACT
    "Langerhans cell granulomatosis" EXACT
    "Letterer-Siwe disease" EXACT
    "Letterer-Siwe disease involving intra-abdominal lymph nodes" EXACT
    "Letterer-Siwe disease involving intrapelvic lymph nodes" EXACT
    "Letterer-Siwe disease involving intrathoracic lymph nodes" EXACT
    "Letterer-Siwe disease involving lymph nodes of axilla and upper limb" EXACT
    "Letterer-Siwe disease involving lymph nodes of head, face and neck" EXACT
    "Letterer-Siwe disease involving lymph nodes of head, face, and neck" EXACT
    "Letterer-Siwe disease involving lymph nodes of inguinal region and lower limb" EXACT
    "Letterer-Siwe disease involving lymph nodes of multiple sites" EXACT
    "Letterer-Siwe disease involving spleen" EXACT
    "Letterer-Siwe disease of intra-abdominal lymph nodes" EXACT
    "Letterer-Siwe disease of intrapelvic lymph nodes" EXACT
    "Letterer-Siwe disease of intrathoracic lymph nodes" EXACT
    "Letterer-Siwe disease of lymph nodes of axilla and upper limb" EXACT
    "Letterer-Siwe disease of lymph nodes of axilla and/or upper limb" EXACT
    "Letterer-Siwe disease of lymph nodes of head, face and neck" EXACT
    "Letterer-Siwe disease of lymph nodes of head, face and/or neck" EXACT
    "Letterer-Siwe disease of lymph nodes of inguinal region amd/or lower limb" EXACT
    "Letterer-Siwe disease of lymph nodes of inguinal region and lower limb" EXACT
    "Letterer-Siwe disease of lymph nodes of inguinal region and/or lower limb" EXACT
    "Letterer-Siwe disease of lymph nodes of multiple sites" EXACT
    "Letterer-Siwe disease of spleen" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
ICD10CM:C96.0
ICD10CM:C96.6
ICD9CM:202.5
ICDO:9751/1
MESH:C538636
MESH:D006646
MIM:246400
MIM:604856
NCI:C3107
NCI:C3160
SNOMEDCT_US_2023_03_01:154583006
SNOMEDCT_US_2023_03_01:234439008
UMLS_CUI:C0019621
UMLS_CUI:C0023381