FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term high grade glioma ID (Ontology) DOID:3070 (Human Disease)
Definition A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.
Also Known As "glial cell tumor" ; "glioma, malignant" ; "malignant glioma" (for all, see Synonyms field below)
Comment
Links to External Ontologies
DO.org
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  HUMAN_DISEASE_INTERACTIONS      91
Human Disease Models (FBhh)  DOID       8
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Human Disease Models
 high grade glioma      96     62      8
 ameliorates | high grade glioma      73       --       --
 exacerbates | high grade glioma       9       --       --
 model of | high grade glioma      17       --       --
 DOES NOT ameliorate | high grade glioma       2       --       --
Spanning Tree (Parents/Children)
Only view relationship:
  cancer
   |__cell type cancer
       |__high grade glioma  193 rec.
           |__brain stem glioma
           |   |__adult brain stem glioma(+)
           |   |__brain stem astrocytic neoplasm
           |__cerebellar astrocytoma
           |   |__childhood cerebellar astrocytic neoplasm
           |   |__pilocytic astrocytoma of cerebellum
           |__chordoid glioma
           |__diencephalic astrocytoma
           |__diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype
           |__high grade ependymoma
           |   |__anaplastic ependymoma
           |   |__brain stem ependymoma
           |   |__childhood ependymoma
           |   |__malignant adult ependymoma
           |   |__posterior fossa ependymoma(+)
           |   |__spinal cord ependymoma(+)
           |   |__supratentorial ependymoma(+)
           |__histone mutated tumor 6 rec.
           |   |__diffuse glioma, H3 G34 mutant
           |   |__diffuse midline glioma, H3 K27M-mutant 6 rec.
           |__malignant astrocytoma 27 rec.
           |   |__adult astrocytic tumor(+)
           |   |__anaplastic astrocytoma(+)
           |   |__anaplastic pleomorphic xanthoastrocytoma(+)
           |   |__astroblastoma(+)
           |   |__childhood astrocytic tumor
           |   |__fibrillary astrocytoma
           |   |__gemistocytic astrocytoma
           |   |__glioblastoma(+) 27 rec.
           |   |__gliofibroma
           |   |__infant-type hemispheric glioma
           |   |__protoplasmic astrocytoma
           |__mixed glioma
           |   |__mixed astrocytoma-ependymoma
           |   |__mixed astrocytoma-ependymoma-oligodendroglioma
           |   |__mixed oligodendroglioma-astrocytoma
           |__oligodendroglioma
           |   |__adult oligodendroglioma
           |   |__anaplastic oligodendroglioma(+)
           |   |__childhood oligodendroglioma
           |   |__corpus callosum oligodendroglioma
           |   |__spinal cord oligodendroglioma
           |__optic nerve astrocytoma
           |   |__childhood optic tract astrocytoma
           |__pineal gland astrocytoma
           |__spinal cord glioma
               |__adult spinal cord glioblastoma multiforme
               |__brain stem ependymoma
               |__spinal cord astrocytoma
               |__spinal cord ependymoma(+)
               |__spinal cord oligodendroglioma
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a cell type cancer
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "glial cell tumor" EXACT
    "glioma, malignant" EXACT
    "malignant glioma" EXACT
    "malignant Neuroglial tumor" EXACT
    "Neuroglial tumor" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
ICDO:9380/3
KEGG:05214
MESH:D005910
MIM:PS137800
NCI:C3059
NCI:C4822
ORDO:182067
SNOMEDCT_US_2023_03_01:393564001
SNOMEDCT_US_2023_03_01:74532006
UMLS_CUI:C0017638
UMLS_CUI:C0555198