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| General Information | |||
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| Term | chronic obstructive pulmonary disease | ID (Ontology) | DOID:3083 (Human Disease) |
| Definition | An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both. | ||
| Also Known As | "chronic obstructive airway disease" ; "chronic obstructive lung disease" ; "COLD" (for all, see Synonyms field below) | ||
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| DO.org | |||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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lung disease |__obstructive lung disease |__chronic obstructive pulmonary disease 1 rec. |__pulmonary emphysema |__compensatory emphysema |__pulmonary interstitial emphysema |
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| Is a | obstructive lung disease | ||
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External Crossreferences & Linkouts
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EFO:0000341 ICD10CM:J44.9 MESH:D029424 MIM:606963 NCI:C3199 SNOMEDCT_US_2023_03_01:13645005 UMLS_CUI:C0024117 |
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