FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term primary ovarian insufficiency ID (Ontology) DOID:5426 (Human Disease)
Definition An ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40.
Also Known As "hypergonadotropic hypogonadism" ; "premature ovarian failure" ; "premature ovarian insufficiency"
Comment
Links to External Ontologies
DO.org
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  HUMAN_DISEASE_INTERACTIONS      23
Human Disease Models (FBhh)  DOID       2
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Human Disease Models
 primary ovarian insufficiency      23     19      2
 ameliorates | primary ovarian insufficiency       4       --       --
 model of | primary ovarian insufficiency      19       --       --
Spanning Tree (Parents/Children)
Only view relationship: 
gonadal disease_____________________
female reproductive system disease__|
                                    ovarian disease
                                     |__primary ovarian insufficiency  62 rec.
                                         |__primary ovarian insufficiency 1 1 rec.
                                         |__primary ovarian insufficiency 2A 1 rec.
                                         |__primary ovarian insufficiency 2B
                                         |__primary ovarian insufficiency 3 2 rec.
                                         |__primary ovarian insufficiency 4
                                         |__primary ovarian insufficiency 5
                                         |__primary ovarian insufficiency 6 1 rec.
                                         |__primary ovarian insufficiency 7 2 rec.
                                         |__primary ovarian insufficiency 8 2 rec.
                                         |__primary ovarian insufficiency 9 2 rec.
                                         |__primary ovarian insufficiency 10 1 rec.
                                         |__primary ovarian insufficiency 11
                                         |__primary ovarian insufficiency 12
                                         |__primary ovarian insufficiency 13 2 rec.
                                         |__primary ovarian insufficiency 14
                                         |__primary ovarian insufficiency 15 1 rec.
                                         |__primary ovarian insufficiency 16 2 rec.
                                         |__primary ovarian insufficiency 17 1 rec.
                                         |__primary ovarian insufficiency 18
                                         |__primary ovarian insufficiency 19
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a ovarian disease
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "hypergonadotropic hypogonadism" EXACT
    "premature ovarian failure" EXACT
    "premature ovarian insufficiency" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
ICD10CM:E28.3
MESH:D016649
MIM:PS311360
NCI:C113352
ORDO:619
SNOMEDCT_US_2023_03_01:237788002
UMLS_CUI:C0085215