FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term complement deficiency ID (Ontology) DOID:626 (Human Disease)
Definition A primary immunodeficiency disease that is the result in a mutation of a gene encoding one of the thirty complement system proteins, produced predominantly in liver, which function to defend against infection and produce inflammation.
Also Known As "Complement deficiency disease"
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  immune system disease
   |__primary immunodeficiency disease
       |__complement deficiency  3 rec.
           |__atypical hemolytic-uremic syndrome
           |__C1 inhibitor deficiency
           |__complement component 2 deficiency
           |__complement component 3 deficiency 3 rec.
           |__complement component 4a deficiency 3 rec.
           |__complement component 4b deficiency 3 rec.
           |__complement component 5 deficiency 3 rec.
           |__complement component 6 deficiency
           |__complement component 7 deficiency
           |__complement component 9 deficiency
           |__complement factor I deficiency
           |__type I complement component 8 deficiency
           |__type II complement component 8 deficiency
           |__X-linked properdin deficiency
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Is a primary immunodeficiency disease
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Synonyms
  • "Complement deficiency disease" EXACT
Secondary IDs
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ICD10CM:D84.1
MESH:D000081208
NCI:C4691
SNOMEDCT_US_2023_03_01:191014008
UMLS_CUI:C0272242