FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term progressive multifocal leukoencephalopathy ID (Ontology) DOID:643 (Human Disease)
Definition A viral infectious disease that involves reactivation of JC polyomavirus (Betapolyomavirus secuhominis) in immune-compromised individuals which causes the loss of white matter (which is made up of myelin, a substance the surrounds and protects nerve fibers) in multiple areas of the brain. The symptoms include hemiparesis, aphasia, dysarthria, hemianopia, cognitive impairment and coma.
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   |__viral infectious disease
       |__progressive multifocal leukoencephalopathy
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Synonyms
  • "PML" RELATED OMO:0003012
Secondary IDs
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GARD:7468
ICD10CM:A81.2
ICD9CM:046.3
MESH:D007968
NCI:C26815
SNOMEDCT_US_2023_03_01:22255007
UMLS_CUI:C0023524