General Information
Term	autoimmune lymphoproliferative syndrome	ID (Ontology)	DOID:6688 (Human Disease)
Definition	A hypersensitivity reaction type IV disease that is an inherited disorder in which the body cannot properly regulate the number of immune system cells (lymphocytes). It is characterized by the production of an abnormally large number of lymphocytes. Accumulation of excess lymphocytes results in enlargement of the lymph nodes, the liver, and the spleen.
Also Known As	"ALPS" ; "Canale-Smith syndrome"
Comment
Links to External Ontologies
	DO.org
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Records annotated with this term OR any of its CHILD TERMS
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General Information

Term

autoimmune lymphoproliferative syndrome

ID (Ontology)

DOID:6688 (Human Disease)

Definition

A hypersensitivity reaction type IV disease that is an inherited disorder in which the body cannot properly regulate the number of immune system cells (lymphocytes). It is characterized by the production of an abnormally large number of lymphocytes. Accumulation of excess lymphocytes results in enlargement of the lymph nodes, the liver, and the spleen.

Also Known As

"ALPS" ; "Canale-Smith syndrome"

Comment

Links to External Ontologies

DO.org

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

  hypersensitivity reaction disease
   |__hypersensitivity reaction type IV disease
       |__autoimmune lymphoproliferative syndrome  5 rec.
           |__autoimmune lymphoproliferative syndrome type 2A 1 rec.
           |__autoimmune lymphoproliferative syndrome type 2B 2 rec.
           |__autoimmune lymphoproliferative syndrome type 3 1 rec.
           |__autoimmune lymphoproliferative syndrome type 4 1 rec.

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Relationships
Is a	hypersensitivity reaction type IV disease
Part of
Synonyms & Secondary IDs
Synonyms
	"ALPS" EXACT OMO:0003012 "Canale-Smith syndrome" EXACT
Secondary IDs

External Crossreferences & Linkouts
	GARD:8686 ICD10CM:D89.82 ICD9CM:279.41 MESH:D056735 MIM:601859 NCI:C37864 ORDO:3261 SNOMEDCT_US_2023_03_01:702444009 UMLS_CUI:C1328840

Spanning Tree View Settings

Parents/Children
View Depth

Relationships

Is a

hypersensitivity reaction type IV disease

Part of

Synonyms & Secondary IDs

Synonyms

"ALPS" EXACT OMO:0003012
"Canale-Smith syndrome" EXACT

Secondary IDs

External Crossreferences & Linkouts

GARD:8686
ICD10CM:D89.82
ICD9CM:279.41
MESH:D056735
MIM:601859
NCI:C37864
ORDO:3261
SNOMEDCT_US_2023_03_01:702444009
UMLS_CUI:C1328840