FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term nervous system disease ID (Ontology) DOID:863 (Human Disease)
Definition A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system.
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Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Alleles (FBal)  HUMAN_DISEASE_INTERACTIONS      54
Human Disease Models (FBhh)  DOID      10
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Relevant FlyBase reports
 Alleles Genes Human Disease Models
 nervous system disease      56     37     10
 ameliorates | nervous system disease      22       --       --
 exacerbates | nervous system disease      13       --       --
 model of | nervous system disease      26       --       --
Spanning Tree (Parents/Children)
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  disease
   |__disease of anatomical entity
       |__nervous system disease  9628 rec.
           |__arthrogryposis multiplex congenita 5 rec.
           |   |__arthrogryposis multiplex congenita-1
           |   |__arthrogryposis multiplex congenita-3 1 rec.
           |   |__arthrogryposis multiplex congenita-4 2 rec.
           |   |__arthrogryposis multiplex congenita-5 1 rec.
           |   |__arthrogryposis multiplex congenita-6
           |   |__neurogenic-type arthrogryposis multiplex congenita-2 1 rec.
           |__autoimmune disease of the nervous system
           |   |__autoimmune disease of central nervous system(+)
           |   |__autoimmune disease of eyes, ear, nose and throat(+)
           |   |__autoimmune disease of peripheral nervous system(+)
           |   |__myasthenia gravis(+)
           |__Behr syndrome 1 rec.
           |__central nervous system disease 8536 rec.
           |   |__angiostrongyliasis
           |   |__autoimmune disease of central nervous system(+)
           |   |__borna disease
           |   |__brain disease(+) 2616 rec.
           |   |__central nervous system benign neoplasm(+) 1 rec.
           |   |__central nervous system cancer(+) 532 rec.
           |   |__central nervous system tuberculosis
           |   |__central nervous system vasculitis(+)
           |   |__coenurosis
           |   |__cysticercosis
           |   |__demyelinating disease(+)
           |   |__encephalomyelitis(+)
           |   |__epidural abscess
           |   |__hemiplegia(+) 2 rec.
           |   |__high pressure neurological syndrome
           |   |__intracranial abscess
           |   |__meningitis(+)
           |   |__meningoencephalitis
           |   |__neurodegenerative disease(+) 7184 rec.
           |   |__neuronitis
           |   |__paralytic poliomyelitis(+)
           |   |__paraplegia(+) 198 rec.
           |   |__primary amebic meningoencephalitis(+)
           |   |__quadriplegia
           |   |__restless legs syndrome 6 rec.
           |   |__spinal cord disease(+)
           |   |__strongyloidiasis
           |   |__subdural empyema
           |__congenital nervous system abnormality 149 rec.
           |   |__anencephaly(+) 1 rec.
           |   |__holoprosencephaly(+) 12 rec.
           |   |__lissencephaly(+) 21 rec.
           |   |__microcephaly(+) 111 rec.
           |   |__periventricular nodular heterotopia 3 rec.
           |   |__subcortical band heterotopia 1 rec.
           |   |__tubulinopathy
           |__diplegia of upper limb
           |__dopamine beta-hydroxylase deficiency 1 rec.
           |__Gerstmann syndrome
           |__herpes zoster
           |   |__Ramsay Hunt syndrome
           |__hyperekplexia 18 rec.
           |   |__hyperekplexia 1 8 rec.
           |   |__hyperekplexia 2 7 rec.
           |   |__hyperekplexia 3 8 rec.
           |   |__hyperekplexia 4 2 rec.
           |__locked-in syndrome
           |__nervous system benign neoplasm 1 rec.
           |   |__central nervous system benign neoplasm(+) 1 rec.
           |   |__neuroma(+)
           |   |__sensory organ benign neoplasm(+)
           |__nervous system cancer 551 rec.
           |   |__central nervous system cancer(+) 532 rec.
           |   |__neuroectodermal tumor(+)
           |   |__peripheral nervous system neoplasm(+) 20 rec.
           |   |__sensory system cancer(+) 2 rec.
           |__neuroaspergillosis
           |__neuroleptic malignant syndrome
           |__peripheral nervous system disease 444 rec.
           |   |__autoimmune disease of peripheral nervous system(+)
           |   |__autonomic nervous system disease(+) 3 rec.
           |   |__Cauda equina syndrome
           |   |__hemangioma of peripheral nerve
           |   |__lumbosacral plexus lesion
           |   |__nerve compression syndrome(+) 2 rec.
           |   |__neuropathy(+) 420 rec.
           |   |__peripheral nervous system neoplasm(+) 20 rec.
           |   |__peroneal nerve paralysis
           |   |__polyneuropathy(+) 2 rec.
           |   |__polyradiculoneuropathy
           |   |__radiculopathy(+)
           |__sensory system disease 803 rec.
           |   |__auditory system disease(+) 183 rec.
           |   |__autoimmune disease of eyes, ear, nose and throat(+)
           |   |__eye disease(+) 624 rec.
           |   |__Leber congenital amaurosis with early-onset deafness 3 rec.
           |   |__sensory organ benign neoplasm(+)
           |   |__sensory system cancer(+) 2 rec.
           |__toxic encephalopathy
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ICD10CM:G98
ICD9CM:349.9
MESH:D009422
NCI:C26835
SNOMEDCT_US_2023_03_01:155262005
UMLS_CUI:C0027765