FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term amyloidosis ID (Ontology) DOID:9120 (Human Disease)
Definition A disease of metabolism that is characterized by extracellular tissue deposition of mis-folded amyloid fibrils built up by twisted protofilaments, deposited in the spaces between the cells of vital organs, causing disruption of organ tissue structure and function. These deposits may result in a wide range of clinical manifestations depending upon their type, location, and the amount of deposition.
Also Known As "amyloid disease"
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Data Class Field Records
Alleles (FBal)  HUMAN_DISEASE_INTERACTIONS      17
Human Disease Models (FBhh)  DOID       1
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 Alleles Genes Human Disease Models
 amyloidosis      17      7      1
 ameliorates | amyloidosis       3       --       --
 model of | amyloidosis      14       --       --
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  disease
   |__disease of metabolism
       |__amyloidosis  61 rec.
           |__apolipoprotein A-IV associated amyloidosis
           |__cerebral amyloid angiopathy 11 rec.
           |   |__APP-related cerebral amyloid angiopathy 2 rec.
           |   |__CST3-related cerebral amyloid angiopathy 3 rec.
           |   |__ITM2B-related cerebral amyloid angiopathy 1 3 rec.
           |   |__ITM2B-related cerebral amyloid angiopathy 2 3 rec.
           |__dialysis-related amyloidosis
           |__familial visceral amyloidosis 4 rec.
           |__immunoglobulin heavy chain amyloidosis
           |__immunoglobulin heavy-and-light chain
           |__immunoglobulin light chain amyloidosis
           |__primary cutaneous amyloidosis 2 rec.
           |   |__Finnish type amyloidosis 2 rec.
           |   |__primary localized cutaneous amyloidosis 1
           |   |__primary localized cutaneous amyloidosis 2
           |   |__primary localized cutaneous amyloidosis 3
           |__serum amyloid A amyloidosis
           |__transthyretin amyloidosis 24 rec.
           |__variant ABeta2M amyloidosis
           |__wild-type amyloidosis
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Synonyms
  • "amyloid disease" EXACT
Secondary IDs
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ICD10CM:E85
ICD9CM:277.3
MESH:D000686
NCI:C2868
SNOMEDCT_US_2023_03_01:154769007
UMLS_CUI:C0002726