FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term brain disease ID (Ontology) DOID:936 (Human Disease)
Definition A central nervous system disease that is located_in the brain.
Also Known As "encephalopathy"
Comment
Links to External Ontologies
DO.org
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  HUMAN_DISEASE_INTERACTIONS       8
Human Disease Models (FBhh)  DOID       2
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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Relevant FlyBase reports
 Alleles Genes Human Disease Models
 brain disease       8      4      2
 ameliorates | brain disease       1       --       --
 model of | brain disease       7       --       --
Spanning Tree (Parents/Children)
Only view relationship:
  nervous system disease
   |__central nervous system disease
       |__brain disease  2616 rec.
           |__akinetic mutism
           |__alveolar echinococcosis
           |__Athabaskan brainstem dysgenesis syndrome 1 rec.
           |__basal ganglia disease 7 rec.
           |   |__basal ganglia calcification 5 rec.
           |   |__biotin-responsive basal ganglia disease 2 rec.
           |__baylisascariasis
           |__brain cancer 474 rec.
           |   |__atypical teratoid rhabdoid tumor 187 rec.
           |   |__brain germinoma(+)
           |   |__brain glioma(+) 54 rec.
           |   |__brain meningioma(+)
           |   |__brain sarcoma(+)
           |   |__childhood central nervous system mixed germ cell tumor
           |   |__childhood CNS embryonal cell carcinoma
           |   |__childhood germ cell brain tumor
           |   |__gliomatosis cerebri
           |   |__infratentorial cancer(+) 5 rec.
           |   |__malignant extragonadal nonseminomatous germ cell tumor
           |   |__supratentorial cancer(+)
           |__brain compression
           |__brain edema
           |__brain small vessel disease 3 rec.
           |   |__brain small vessel disease 1 2 rec.
           |   |__brain small vessel disease 2 1 rec.
           |   |__brain small vessel disease 3 1 rec.
           |__central nervous system origin vertigo
           |__cerebellar disease 1095 rec.
           |   |__cerebellar ataxia(+) 1092 rec.
           |   |__cerebellar hypoplasia 2 rec.
           |   |__cerebellum cancer(+)
           |   |__Dandy-Walker syndrome
           |   |__L-2-hydroxyglutaric aciduria 1 rec.
           |__cerebral degeneration 111 rec.
           |   |__cerebral lipidosis
           |   |__hydrocephalus(+) 6 rec.
           |   |__leukodystrophy(+) 103 rec.
           |   |__neuroaxonal dystrophy(+)
           |   |__senile degeneration of brain
           |__cerebral palsy 13 rec.
           |   |__ataxic cerebral palsy
           |   |__dyskinetic cerebral palsy
           |   |__mixed cerebral palsy
           |   |__spastic cerebral palsy(+) 10 rec.
           |__cerebritis
           |__cerebrovascular disease 30 rec.
           |   |__anterior spinal artery syndrome
           |   |__arteriovenous malformations of the brain 1 rec.
           |   |__basal ganglia cerebrovascular disease
           |   |__brain angioma(+)
           |   |__brain infarction(+) 1 rec.
           |   |__brain ischemia(+) 14 rec.
           |   |__carotid artery disease(+)
           |   |__cerebral arteritis
           |   |__cerebral artery occlusion
           |   |__cerebral cavernous malformation(+) 2 rec.
           |   |__intracranial arterial disease(+) 12 rec.
           |   |__intracranial embolism
           |   |__intracranial thrombosis(+)
           |   |__intracranial vasospasm
           |   |__occlusion precerebral artery(+)
           |__complex cortical dysplasia with other brain malformations 23 rec.
           |   |__bilateral frontoparietal polymicrogyria 2 rec.
           |   |__complex cortical dysplasia with other brain malformations 1 5 rec.
           |   |__complex cortical dysplasia with other brain malformations 2 1 rec.
           |   |__complex cortical dysplasia with other brain malformations 3 1 rec.
           |   |__complex cortical dysplasia with other brain malformations 4 2 rec.
           |   |__complex cortical dysplasia with other brain malformations 5 2 rec.
           |   |__complex cortical dysplasia with other brain malformations 6 3 rec.
           |   |__complex cortical dysplasia with other brain malformations 7 2 rec.
           |   |__complex cortical dysplasia with other brain malformations 9 1 rec.
           |   |__complex cortical dysplasia with other brain malformations 10 2 rec.
           |   |__complex cortical dysplasia with other brain malformations 11 1 rec.
           |   |__complex cortical dysplasia with other brain malformations 12 1 rec.
           |   |__complex cortical dysplasia with other brain malformations 13 2 rec.
           |   |__pachygyria, microcephaly, developmental delay, and dysmorphic facies, with or without seizures 5 rec.
           |__congenital variant of Rett syndrome 5 rec.
           |__cortical dysplasia-focal epilepsy syndrome 3 rec.
           |__cystic echinococcosis
           |__diabetic encephalopathy
           |__Eastern equine encephalitis
           |__encephalitis
           |   |__acute hemorrhagic encephalitis
           |   |__acute necrotizing encephalitis
           |   |__limbic encephalitis
           |   |__post-vaccinal encephalitis
           |   |__postinfectious encephalitis
           |   |__syphilitic encephalitis
           |   |__viral encephalitis(+)
           |   |__von Economo's disease
           |__encephalomalacia
           |   |__periventricular leukomalacia
           |__epilepsy 551 rec.
           |   |__autoimmune epilepsy
           |   |__early-onset epilepsy 2 1 rec.
           |   |__early-onset epilepsy 3 7 rec.
           |   |__electroclinical syndrome(+) 264 rec.
           |   |__extratemporal epilepsy
           |   |__focal epilepsy(+) 37 rec.
           |   |__generalized epilepsy(+) 24 rec.
           |   |__photosensitive epilepsy 11 rec.
           |   |__pyridoxine-dependent epilepsy(+) 2 rec.
           |   |__status epilepticus
           |   |__visual epilepsy
           |   |__X-linked epilepsy with variable learning disabilities and behavior disorders 1 rec.
           |__familial febrile seizures 12 rec.
           |   |__familial febrile seizures 1
           |   |__familial febrile seizures 2 1 rec.
           |   |__familial febrile seizures 4
           |   |__familial febrile seizures 5
           |   |__familial febrile seizures 6
           |   |__familial febrile seizures 7
           |   |__familial febrile seizures 8 2 rec.
           |   |__familial febrile seizures 9
           |   |__familial febrile seizures 10
           |   |__familial febrile seizures 11 9 rec.
           |__frontotemporal dementia 180 rec.
           |   |__corticobasal degeneration syndrome
           |   |__frontotemporal dementia and/or amyotrophic lateral sclerosis 7 41 rec.
           |   |__GRN-related frontotemporal lobar degeneration with Tdp43 inclusions
           |   |__Pick's disease 6 rec.
           |   |__primary progressive aphasia(+)
           |__granulomatous amebic encephalitis
           |__hepatic encephalopathy
           |   |__hepatic coma
           |__heterophyiasis
           |__homocarnosinosis
           |__hypoglycemic coma
           |__hypothalamic disease
           |   |__Froelich syndrome
           |   |__hypothalamic neoplasm
           |__infantile cerebral and cerebellar atrophy with postnatal progressive microcephaly 1 rec.
           |__intracranial hypertension
           |   |__hypertensive encephalopathy
           |   |__pseudotumor cerebri
           |__intracranial hypotension
           |__Japanese encephalitis 2 rec.
           |__Joubert syndrome 15 rec.
           |   |__Joubert syndrome 1 1 rec.
           |   |__Joubert syndrome 2 2 rec.
           |   |__Joubert syndrome 3
           |   |__Joubert syndrome 4
           |   |__Joubert syndrome 5 1 rec.
           |   |__Joubert syndrome 6 1 rec.
           |   |__Joubert syndrome 7
           |   |__Joubert syndrome 8
           |   |__Joubert syndrome 9 1 rec.
           |   |__Joubert syndrome 10
           |   |__Joubert syndrome 13 1 rec.
           |   |__Joubert syndrome 14
           |   |__Joubert syndrome 15
           |   |__Joubert syndrome 16 1 rec.
           |   |__Joubert syndrome 17
           |   |__Joubert syndrome 18 1 rec.
           |   |__Joubert syndrome 20 1 rec.
           |   |__Joubert syndrome 21
           |   |__Joubert syndrome 22 1 rec.
           |   |__Joubert syndrome 23
           |   |__Joubert syndrome 24
           |   |__Joubert syndrome 25 1 rec.
           |   |__Joubert syndrome 26
           |   |__Joubert syndrome 27 1 rec.
           |   |__Joubert syndrome 28 1 rec.
           |   |__Joubert syndrome 29
           |   |__Joubert syndrome 30
           |   |__Joubert syndrome 31 1 rec.
           |   |__Joubert syndrome 32 1 rec.
           |   |__Joubert syndrome 33
           |   |__Joubert syndrome with orofaciodigital defect
           |__kernicterus
           |__La Crosse encephalitis
           |__low grade glioma
           |   |__angiocentric glioma
           |   |__benign ependymoma(+)
           |   |__childhood low-grade glioma(+)
           |   |__diffuse astrocytoma(+)
           |   |__diffuse low-grade glioma, MAPK pathway–altered
           |   |__pleomorphic xanthoastrocytoma
           |__lymphocytic choriomeningitis
           |__MASA syndrome 6 rec.
           |__migraine 21 rec.
           |   |__migraine with aura(+) 20 rec.
           |   |__migraine without aura
           |__movement disease 120 rec.
           |   |__benign shuddering attacks
           |   |__choreatic disease(+) 1 rec.
           |   |__congenital mirror movement disorder(+) 6 rec.
           |   |__dopamine transporter deficiency syndrome(+) 12 rec.
           |   |__dystonia(+) 77 rec.
           |   |__essential tremor(+) 12 rec.
           |   |__extrapyramidal and movement disease 2 rec.
           |   |__infantile parkinsonism-dystonia 2 1 rec.
           |   |__lingual-facial-buccal dyskinesia
           |   |__neurodevelopmental disorder with involuntary movements 1 rec.
           |   |__Parkinsonism(+)
           |   |__progressive supranuclear palsy 7 rec.
           |   |__Stiff-Person syndrome
           |   |__X-linked parkinsonism-spasticity syndrome 1 rec.
           |__Murray Valley encephalitis
           |__neuroschistosomiasis
           |__paragonimiasis
           |__PEHO syndrome 1 rec.
           |__polymicrogyria 3 rec.
           |   |__bilateral frontal polymicrogyria
           |   |__bilateral generalized polymicrogyria
           |   |__bilateral parasagittal parieto-occipital polymicrogyria 1 rec.
           |   |__bilateral perisylvian polymicrogyria 2 rec.
           |   |__unilateral focal polymicrogyria
           |__porencephaly
           |__prion disease 90 rec.
           |   |__chronic wasting disease
           |   |__Creutzfeldt-Jakob disease 13 rec.
           |   |__fatal familial insomnia 2 rec.
           |   |__Gerstmann-Straussler-Scheinker syndrome 5 rec.
           |   |__Huntington's disease-like 1
           |   |__kuru
           |   |__scrapie 8 rec.
           |   |__variant Creutzfeldt-Jakob disease
           |__pseudobulbar palsy
           |__severe congenital encephalopathy due to MECP2 mutation 2 rec.
           |__sparganosis
           |__tertiary neurosyphilis
           |   |__asymptomatic neurosyphilis
           |   |__meningovascular neurosyphilis
           |   |__parenchymatous neurosyphilis
           |   |__tabes dorsalis
           |__thalamic disease
           |__toxocariasis
           |__traumatic brain injury 1 rec.
           |__Wernicke encephalopathy
           |__West Nile encephalitis
           |   |__Kunjin encephalitis
           |__Western equine encephalitis
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Synonyms
  • "encephalopathy" EXACT
Secondary IDs
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ICD10CM:G93.40
ICD10CM:G93.9
ICD9CM:348.30
ICD9CM:348.9
MESH:D001927
NCI:C26920
NCI:C96413
SNOMEDCT_US_2023_03_01:81308009
UMLS_CUI:C0006111
UMLS_CUI:C0085584