FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term mesoderm ID (Ontology) FBbt:00000126 (Fly Anatomy)
Definition Middle germ layer of the embryo (between ectoderm and endoderm) following gastrulation (Campos-Ortega and Hartenstein, 1997). Shortly after its formation, its cells undergo mitosis and it loses its regular epithelial architecture (Campos-Ortega and Hartenstein, 1997). In stage 9 it reorganizes into a regular monolayer of cuboidal cells that lines the ectoderm (Campos-Ortega and Hartenstein, 1997). At the end of stage 10 further cell divisions disrupt this structure and its cells reform into two layers in stage 11 (Campos-Ortega and Hartenstein, 1997). It finally splits up into separate cell masses in late stage 11 (Campos-Ortega and Hartenstein, 1997). Its derivatives include the muscles, heart and fat body (Campos-Ortega and Hartenstein, 1997).[ FlyBase:FBrf0089570 FlyBase:FBrf0155831 ]
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Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN     106
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION      63
Insertions (FBti)  PHENOTYPE_MANIFEST_IN      10
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN      46
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 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Images Insertions Constructs
 mesoderm (all annotations which use CV term, excluding "NOT" statements)     107    225     13     73    117
     mesoderm | absent       1       --       --       --       --
     mesoderm | dorsal       6       --       --       --       1
     mesoderm | ectopic       3       --       --       --       2
     mesoderm | embryonic stage       5       --       --       1      2
     mesoderm | embryonic stage 8       5       --       --       --       5
     mesoderm | embryonic stage | maternal effect | ventral       1       --       --       1       --
     mesoderm | germline clone      10       --       --       4       --
     mesoderm | germline clone | maternal effect       1       --       --       --       --
     mesoderm | germline clone | non-rescuable maternal effect       1       --       --       --       --
     mesoderm | heat sensitive       1       --       --       --       --
     mesoderm | maternal effect       6       --       --       --       3
Spanning Tree (Parents/Children)
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developing embryonic structure__
primordium______________________|
portion of tissue_______________|
                                germ layer
                                 |__mesoderm  1987 rec.
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Is a germ layer
Develops from mesoderm anlage
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UBERON:0000926