FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term Usib neuron ID (Ontology) FBbt:00001568 (Fly Anatomy)
Definition Notch OFF sibling neuron to a U neuron (MN-DO1, -DA2, -DO2, -DA3 and -LL1) deriving from a ganglion mother cell from the neuroblast 7-1 during embryogenesis (Seroka et al., 2020). Differentiation from the ganglion mother cell initially produces eve (FBgn0000606) positive cells. Whereas the U neurons (MN-DO1, -DA2, -DO2, -DA3 and -LL1) remain eve positive, the Usib cell rapidly downregulates eve.[ FlyBase:FBrf0102831 FlyBase:FBrf0162056 FlyBase:FBrf0246311 ]
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VFB:FBbt_00001568
Annotations
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Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN      13
Insertions (FBti)  PHENOTYPE_MANIFEST_IN       1
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN       3
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Relevant FlyBase reports
 Alleles Insertions Constructs
 Usib neuron (all annotations which use CV term, excluding "NOT" statements)      13      1      3
     Usib neuron | germline clone       5       --       --
Spanning Tree (Parents/Children)
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Notch OFF hemilineage primary neuron__
NB7-1 lineage primary neuron__________|
                                      NB7-1 Notch OFF hemilineage primary neuron
                                       |__Usib neuron  17 rec.
                                           |__A1-7 DA2sib neuron
                                           |__A1-7 DA3sib neuron
                                           |__A1-7 DO1sib neuron
                                           |__A1-7 DO2sib neuron
                                           |__A1-7 LL1sib neuron
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Is a NB7-1 Notch OFF hemilineage primary neuron
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VFB:FBbt_00001568