FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term embryonic/larval plasmatocyte ID (Ontology) FBbt:00001685 (Fly Anatomy)
Definition Hemocyte of the embryo and larva. Relatively large, irregularly shaped hemocyte (Brehelin, 1982). At the end of the third instar larval stage, plasmatocytes contains numerous inclusions, digitations and pinocytotic vesicles, well developed rough endoplasmic reticulum, Golgi apparatus and small lysosome-like bodies. By the end of the third instar period they also contain numerous phagosomes. Plasmatocytes represent 90-95% of all mature larval hemocytes. They function in the removal of dead cells and microbial pathogens.[ FlyBase:FBrf0037631 FlyBase:FBrf0066479 FlyBase:FBrf0134542 ]
Also Known As "macrophage" ; "Pl" ; "podocyte"
Comment Brehelin and Zachary (1986) state that they never observe granular inclusions in plasmatocytes. Sometimes a few primary lysosomes as well as rare multivesicular bodies are visible, but these lysosomes are never 'condensed' into electron-dense granules. Together, this suggests that the synonym of 'granulocytes' is erroneous. The term podocyte refers to a plasmatocyte that extends long cytoplasmic extensions. They are no longer recognized as a distinct cell type (Michelle Crozatier, personal communication).
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Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN     239
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       8
Insertions (FBti)  PHENOTYPE_MANIFEST_IN      37
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN     129
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes  Insertions Constructs
 embryonic/larval plasmatocyte (all annotations which use CV term, excluding "NOT" statements)     241    116      8     45    137
     embryonic/larval plasmatocyte | adult stage       4       --       --       --       2
     embryonic/larval plasmatocyte | conditional | larval stage       1       --       --       --       --
     embryonic/larval plasmatocyte | conditional | third instar larval stage       1       --       --       --       --
     embryonic/larval plasmatocyte | decreased number | embryonic stage      10       --       --       --       9
     embryonic/larval plasmatocyte | decreased number | larval stage       2       --       --       --       --
     embryonic/larval plasmatocyte | decreased number | larval stage | conditional       2       --       --       --       2
     embryonic/larval plasmatocyte | ectopic       7       --       --       1      2
     embryonic/larval plasmatocyte | embryonic stage      27       --       --       2     20
     embryonic/larval plasmatocyte | embryonic stage 10       1       --       --       1       --
     embryonic/larval plasmatocyte | embryonic stage 11       1       --       --       1       --
     embryonic/larval plasmatocyte | embryonic stage 12       9       --       --       4      5
     embryonic/larval plasmatocyte | embryonic stage 13       4       --       --       1       --
     embryonic/larval plasmatocyte | embryonic stage 14       2       --       --       1       --
     embryonic/larval plasmatocyte | embryonic stage 15       1       --       --       --       --
     embryonic/larval plasmatocyte | embryonic stage | increased number       2       --       --       1       --
     embryonic/larval plasmatocyte | heat sensitive       3       --       --       --       3
     embryonic/larval plasmatocyte | increased number      13       --       --       --       7
     embryonic/larval plasmatocyte | increased number | larval stage      10       --       --       --       8
     embryonic/larval plasmatocyte | increased number | third instar larval stage       4       --       --       --       1
     embryonic/larval plasmatocyte | larval stage      15       --       --       2     10
     embryonic/larval plasmatocyte | P-stage      10       --       --       --       6
     embryonic/larval plasmatocyte | P-stage | increased number       7       --       --       1      4
     embryonic/larval plasmatocyte | prepupal stage       3       --       --       --       2
     embryonic/larval plasmatocyte | pupal stage       8       --       --       --       7
     embryonic/larval plasmatocyte | third instar larval stage      33       --       --       7     16
Spanning Tree (Parents/Children)
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germ layer derivative
 |__mesodermal derivative______
hemocyte                       |
 |__embryonic/larval hemocyte__|
 |__plasmatocyte_______________|
                               embryonic/larval plasmatocyte  551 rec.
                                |__larval adipohemocyte 4 rec.
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Is a embryonic/larval hemocyte
mesodermal derivative
plasmatocyte
Develops from proplasmatocyte
Part of
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Synonyms
Secondary IDs
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CL:0000394