FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term lamellocyte ID (Ontology) FBbt:00001687 (Fly Anatomy)
Definition Hemocyte of the larva that is large, flat and regularly shaped and is involved encapsulation as part of the immune response. They contain short and narrow vesicles of rough endoplasmic reticulum, a well developed Golgi apparatus and some free ribosomes. Lamellocytes are not found in embryos and adults, and are rare in healthy larvae, although their differentiation can be induced by parasitoid wasp infection. Lamellocytes are involved in encapsulating and killing parasites. They differentiate both from the lymph gland and from the sessile hemocyte population. They express atilla (Cattenoz et al., 2020).[ FlyBase:FBrf0031012 FlyBase:FBrf0037631 FlyBase:FBrf0134542 FlyBase:FBrf0144807 FlyBase:FBrf0207538 FlyBase:FBrf0212461 FlyBase:FBrf0245988 ]
Comment Lamellocytes have been suggested to differentiate from plasmatocytes (Stofanko et al., 2010).
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Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN     134
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       2
Insertions (FBti)  PHENOTYPE_MANIFEST_IN      16
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN      78
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes  Insertions Constructs
 lamellocyte (all annotations which use CV term, excluding "NOT" statements)     136     11      8     18     80
     lamellocyte | cell non-autonomous | larval stage | somatic clone | increased number       1       --       --       --       1
     lamellocyte | cell non-autonomous | somatic clone | third instar larval stage       3       --       --       1      2
     lamellocyte | conditional | larval stage       1       --       --       --       --
     lamellocyte | conditional | third instar larval stage       1       --       --       --       --
     lamellocyte | decreased number       2       --       --       --       2
     lamellocyte | decreased number | larval stage       2       --       --       --       1
     lamellocyte | decreased number | larval stage | conditional       5       --       --       --       5
     lamellocyte | ectopic       4       --       --       --       --
     lamellocyte | heat sensitive       3       --       --       --       3
     lamellocyte | increased number      18       --       --       --       7
     lamellocyte | increased number | larval stage      16       --       --       --      13
     lamellocyte | increased number | larval stage | conditional       4       --       --       --       2
     lamellocyte | increased number | larval stage | somatic clone       1       --       --       --       --
     lamellocyte | increased number | third instar larval stage      13       --       --       --      12
     lamellocyte | larval stage      17       --       --       2      7
     lamellocyte | larval stage | conditional       5       --       --       --       3
     lamellocyte | larval stage | increased number       5       --       --       --       1
     lamellocyte | larval stage | progressive       1       --       --       1       --
     lamellocyte | second instar larval stage | increased number       2       --       --       --       --
     lamellocyte | third instar larval stage      23       --       --       2     17
     lamellocyte | third instar larval stage | conditional       5       --       --       --       4
Spanning Tree (Parents/Children)
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germ layer derivative
 |__mesodermal derivative______
hemocyte                       |
 |__embryonic/larval hemocyte__|
                               lamellocyte  253 rec.
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Is a embryonic/larval hemocyte
mesodermal derivative
Develops from prolamellocyte
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CL:0000396