FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term larval inner optic anlage ID (Ontology) FBbt:00001951 (Fly Anatomy)
Definition A ribbon-like layer of neuroepithelial cells (and later of proliferating neuroblasts) in the larval optic lobe that gives rise to the adult inner medulla, lobula and lobula plate neurons. In early larval stages it is composed of neuroepithelial cells that divide symmetrically. In the early second instar it becomes U shaped, with the opening of the U pointing in a dorso-caudal direction. It becomes distinguished from the outer optic anlage during the second half of the first instar period (Meinertzhagen and Hanson, 1993). In the third instar, neuroepithelial cells in the medial region give rise to neuroblasts that divide asymmetrically to generate the adult optic lobe neurons.[ FlyBase:FBrf0052913 FlyBase:FBrf0193624 ]
Also Known As "embryonic/larval inner optic anlage" ; "IOA"
Comment 'proliferation center' synonyms usually used for later stages of development (Ngo et al., 2017 - FBrf0236058).
Links to External Ontologies
VFB:FBbt_00001951
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN      28
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION      14
Insertions (FBti)  PHENOTYPE_MANIFEST_IN       5
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN      10
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Insertions Constructs
 larval inner optic anlage (all annotations which use CV term, excluding "NOT" statements)      28     18     19     18
     larval inner optic anlage | ectopic | third instar larval stage       5       --       1      1
     larval inner optic anlage | heat sensitive       1       --       --       --
     larval inner optic anlage | precursor       4       --       1       --
     larval inner optic anlage | third instar larval stage       3       --       --       1
Spanning Tree (Parents/Children)
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anlage________________________
anterior ectoderm derivative__|
                              larval optic anlage
                               |__larval inner optic anlage  105 rec.
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Is a larval optic anlage
Develops from embryonic inner optic lobe primordium
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VFB:FBbt_00001951