FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term transmedullary neuron Tm1 ID (Ontology) FBbt:00003789 (Fly Anatomy)
Definition Transmedullary narrow field neuron that terminates in lobula layer 1 with a bleb-type terminal arborization and that has fine arborizations in medulla layer M2 and bleb-type arborizations in M3 and M9 (Fischbach and Dittrich, 1989; Takemura et al., 2011). In the medulla, it receives strong synaptic input from lamina monopolar neuron L2 (Takemura et al., 2011; Takemura et al., 2013). It outputs onto T5 neurons (Shinomiya et al., 2019). It is a cholinergic neuron (Varija Raghu et al., 2011; Shinomiya et al., 2014). There is usually one of these cells per optic column (Nern et al., 2025).[ FlyBase:FBrf0049410 FlyBase:FBrf0204652 FlyBase:FBrf0212356 FlyBase:FBrf0217052 FlyBase:FBrf0222324 FlyBase:FBrf0225094 FlyBase:FBrf0241236 FlyBase:FBrf0262545 ]
Also Known As "Tm1"
Comment The neurotransmitter was assessed by co-labelling cells with a P\{Cha-GAL4.7.4\} driver (FBtp0014830) and an anti-ChAT antibody (Varija Raghu et al., 2011; Shinomiya et al., 2014). Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity in the medulla was extrapolated from serial EM of 3 columns from a single sample (Takemura et al., 2008) or from 7 columns (Takemura et al., 2013). Connectivity in the lobula was assessed by serial section electron microscopy of a single column (Shinomiya et al., 2014). Connectivity in the entire optic lobe was also assessed by EM (Shinomiya et al., 2019).
Links to External Ontologies
VFB:FBbt_00003789
Annotations
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Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN       5
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       2
Insertions (FBti)  PHENOTYPE_MANIFEST_IN       1
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN       5
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Relevant FlyBase reports
 Alleles  Genes  Insertions Constructs
 transmedullary neuron Tm1 (all annotations which use CV term, excluding "NOT" statements)       7      1      2      8      3      8
     transmedullary neuron Tm1 | adult stage       4       --       --       --       --       5
     transmedullary neuron Tm1 | ectopic | somatic clone       1       --       --       --       1       --
Spanning Tree (Parents/Children)
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transmedullary neuron
 |__narrow field transmedullary neuron_____
cholinergic neuron                         |
 |__adult cholinergic neuron_______________|
adult neuron                               |
 |__adult cholinergic neuron_______________|
secondary neuron                           |
 |__Notch ON hemilineage secondary neuron__|
Notch ON hemilineage neuron                |
 |__Notch ON hemilineage secondary neuron__|
optic lobe narrow field columnar neuron    |
 |__narrow field transmedullary neuron_____|
                                           transmedullary neuron Tm1  29 rec.
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Is a narrow field transmedullary neuron
Notch ON hemilineage secondary neuron
adult cholinergic neuron
Develops from immature transmedullary neuron Tm1
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FlyBrain_NDB:10132
VFB:FBbt_00003789