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| Term | proximal medullary amacrine neuron Pm1 | ID (Ontology) | FBbt:00003833 (Fly Anatomy) |
| Definition | Proximal medullary wide-field amacrine neuron that branches as it enters the proximal side of the medulla and forms broad terminal arbors, with mixed pre- and post-synaptic terminals, mainly in medulla layer M9 (Fischbach and Dittrich, 1989; Morante and Desplan, 2008).[ FlyBase:FBrf0049410 FlyBase:FBrf0204652 ] | ||
| Also Known As | "Pm1" | ||
| Comment | Neurotransmitter determined to be acetylcholine based on Cha-GAL4.7.4 driver (FBtp0014830) expression and anti-ChaT staining (Varija Raghu et al., 2011 - FBrf0212356), but scRNAseq data assigns as GABA based on Gad1 transcripts and lineage (Konstantinides et al., 2022 - FBrf0253187). EM also predicts GABA (Nern et al., 2025 - FBrf0262545). Nern et al. (2025) split this into 3 subtypes (Pm1, Pm5, Pm6), which seem to have small differences in layer and column spans. | ||
| Links to External Ontologies | |||
| VFB:FBbt_00003833 | |||
| Annotations | |||
| Records annotated with this term OR any of its CHILD TERMS | |||
Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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supraesophageal ganglion neuron |__adult optic lobe neuron_________________ optic lobe amacrine neuron | |__proximal medullary amacrine neuron______| adult optic lobe columnar neuron | |__optic lobe wide-field columnar neuron___| anterior ectoderm derivative | |__adult optic lobe neuron_________________| secondary neuron | |__Notch OFF hemilineage secondary neuron__| Notch OFF hemilineage neuron | |__Notch OFF hemilineage secondary neuron__| medulla intrinsic neuron | |__proximal medullary amacrine neuron______| adult CNS neuron | |__adult optic lobe neuron_________________| proximal medullary amacrine neuron Pm1 4 rec. |
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| Is a |
adult optic lobe neuron proximal medullary amacrine neuron Notch OFF hemilineage secondary neuron optic lobe wide-field columnar neuron |
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| Develops from | immature proximal medullary amacrine neuron Pm1 | ||
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External Crossreferences & Linkouts
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FlyBrain_NDB:10109 VFB:FBbt_00003833 |
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