FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term proximal medullary amacrine neuron Pm1 ID (Ontology) FBbt:00003833 (Fly Anatomy)
Definition Proximal medullary wide-field amacrine neuron that branches as it enters the proximal side of the medulla and forms broad terminal arbors, with mixed pre- and post-synaptic terminals, mainly in medulla layer M9 (Fischbach and Dittrich, 1989; Morante and Desplan, 2008).[ FlyBase:FBrf0049410 FlyBase:FBrf0204652 ]
Also Known As "Pm1"
Comment Neurotransmitter determined to be acetylcholine based on Cha-GAL4.7.4 driver (FBtp0014830) expression and anti-ChaT staining (Varija Raghu et al., 2011 - FBrf0212356), but scRNAseq data assigns as GABA based on Gad1 transcripts and lineage (Konstantinides et al., 2022 - FBrf0253187). EM also predicts GABA (Nern et al., 2025 - FBrf0262545). Nern et al. (2025) split this into 3 subtypes (Pm1, Pm5, Pm6), which seem to have small differences in layer and column spans.
Links to External Ontologies
VFB:FBbt_00003833
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN       1
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       1
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 Full annotation statements 
Relevant FlyBase reports
 Alleles  Insertions Constructs
 proximal medullary amacrine neuron Pm1 (all annotations which use CV term, excluding "NOT" statements)       1      1      1      1
     proximal medullary amacrine neuron Pm1 | absent | larval stage       1       --       --       --
Spanning Tree (Parents/Children)
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supraesophageal ganglion neuron
 |__adult optic lobe neuron_________________
optic lobe amacrine neuron                  |
 |__proximal medullary amacrine neuron______|
adult optic lobe columnar neuron            |
 |__optic lobe wide-field columnar neuron___|
anterior ectoderm derivative                |
 |__adult optic lobe neuron_________________|
secondary neuron                            |
 |__Notch OFF hemilineage secondary neuron__|
Notch OFF hemilineage neuron                |
 |__Notch OFF hemilineage secondary neuron__|
medulla intrinsic neuron                    |
 |__proximal medullary amacrine neuron______|
adult CNS neuron                            |
 |__adult optic lobe neuron_________________|
                                            proximal medullary amacrine neuron Pm1  4 rec.
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Is a adult optic lobe neuron
proximal medullary amacrine neuron
Notch OFF hemilineage secondary neuron
optic lobe wide-field columnar neuron
Develops from immature proximal medullary amacrine neuron Pm1
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Synonyms
Secondary IDs
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FlyBrain_NDB:10109
VFB:FBbt_00003833