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| Term | giant fiber neuron | ID (Ontology) | FBbt:00004020 (Fly Anatomy) | |||||||||||||||||||||||||||||||||||||||||||||||
| Definition | Large adult descending neuron that controls jump escape behavior (Thomas and Wyman, 1984).There is one of these cells per hemisphere (Koto et al., 1981; Namiki et al., 2018; Sturner et al., 2024) and its large cell body is located posterior to the lower protocerebrum (Koto et al., 1981). It can be identified by its large descending axon (Power, 1948), which is several times larger than any other axon in the cervical connective (Koto et al., 1981). It enters the cervical connective via the posterior cerebro-cervical fascicle (Ito et al., 2014) and descends on the ipsilateral side (Koto et al., 1981; Namiki et al., 2018), in the dorsal cervical fasciculus (Power, 1948). In the brain, it has dendritic arborization in the ipsilateral zones A and B of the antennal mechanosensory and motor center (Kamikouchi et al., 2009; Matsuo et al., 2016), where it receives substantial input from zone A and B Johnston organ neurons (Kim et al., 2020). It also arborizes in the posterior ventrolateral protocerebrum and gorget (Matsuo et al., 2016; Namiki et al., 2018). It enters the VNC near the dorsal midline and extends posteroventrally to the mesothoracic neuromere, where it turns ventrolaterally, and ends abruptly without branching (Koto et al., 1981). In the mesothoracic neuromere, it forms electrical synapses with downstream motor and premotor neurons at the inframedial bridge, where the two giant fiber neurons connect across the midline, and at the axonal lateral bend (King and Wyman, 1980; Allen et al., 1998; Kennedy and Broadie, 2018). It is a primary neuron (Allen et al., 1998; Dorkenwald et al., 2024; Schlegel et al., 2024).[ FlyBase:FBrf0007196 FlyBase:FBrf0035198 FlyBase:FBrf0035908 FlyBase:FBrf0041358 FlyBase:FBrf0044916 FlyBase:FBrf0085744 FlyBase:FBrf0103226 FlyBase:FBrf0207518 FlyBase:FBrf0224194 FlyBase:FBrf0230862 FlyBase:FBrf0239335 FlyBase:FBrf0241174 FlyBase:FBrf0246780 FlyBase:FBrf0260535 FlyBase:FBrf0260546 ] | |||||||||||||||||||||||||||||||||||||||||||||||||
| Also Known As | "AMMC projection neuron, Giant Fiber" ; "aPN(GF)" ; "cervical giant fiber neuron" (for all, see Synonyms field below) | |||||||||||||||||||||||||||||||||||||||||||||||||
| Comment | Some components identified by Power (1948) later found to be electrically-coupled neurons (King and Wyman, 1980; Phelan et al., 1996). | |||||||||||||||||||||||||||||||||||||||||||||||||
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| VFB:FBbt_00004020 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Records annotated with this term OR any of its CHILD TERMS | ||||||||||||||||||||||||||||||||||||||||||||||||||
Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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interneuron |__primary interneuron_______________________ mechanosensory system neuron | |__auditory system neuron____________________| primary neuron | |__primary interneuron_______________________| adult descending neuron | |__descending neuron of the posterior brain__| adult interneuron | |__adult subesophageal sensory interneuron___| CNS neuron | |__supraesophageal ganglion neuron___________| adult CNS neuron | |__descending neuron of the posterior brain__| giant fiber neuron 199 rec. |
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supraesophageal ganglion neuron adult subesophageal sensory interneuron descending neuron of the posterior brain primary interneuron auditory system neuron |
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External Crossreferences & Linkouts
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| VFB:FBbt_00004020 | |||