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General Information
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| Term |
follicle stem cell |
ID (Ontology) |
FBbt:00004903 (Fly Anatomy) |
| Definition |
Stem cell from which the follicle cells that envelop the germline cyst derive. They develop from the larval follicle stem cell progenitors (Slaidina et al., 2020). There are two follicle stem cells in each germarium, located at opposite sides of the lateral wall of the germarium, in between regions 2a and 2b (Reilein et al., 2017). Each follicle stem cell produces over 500 follicle cells from nine cell divisions (Airoldi et al., 2011).[ FlyBase:FBrf0084162 FlyBase:FBrf0202474 FlyBase:FBrf0209788 FlyBase:FBrf0217092 FlyBase:FBrf0235409 FlyBase:FBrf0244767 FlyBase:FBrf0247148 ] |
| Also Known As |
"epithelial follicle stem cell" ; "FSC" |
| Comment |
Can be identified by expression of zfh1, Fas3 and low expression of Wnt4 (Rust et al., 2020). |
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Links to External Ontologies
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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| Data Class | Field | Records |
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| Alleles (FBal) | PHENOTYPE_MANIFEST_IN | 62 | | Insertions (FBti) | EXPRESSION_STAGE_TISSUE_POSITION | 17 | | Insertions (FBti) | PHENOTYPE_MANIFEST_IN | 12 | | Constructs (FBtp) | PHENOTYPE_MANIFEST_IN | 19 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Alleles | Genes | | Insertions | Constructs |
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follicle stem cell (all annotations which use CV term, excluding "NOT" statements) | 62 | 11 | 5 | 29 | 26 | follicle stem cell | heat sensitive | 2 | -- | -- | -- | -- | follicle stem cell | oogenesis | progressive | somatic clone | 2 | -- | -- | -- | -- | follicle stem cell | somatic clone | 50 | -- | -- | 10 | 16 | follicle stem cell | somatic clone | increased number | 1 | -- | -- | -- | -- |
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Relationships