FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term embryonic Malpighian tubule tip cell ID (Ontology) FBbt:00005643 (Fly Anatomy)
Definition Tip cell of the embryonic Malpighian tubule. It persists throughout tubule elongation during stages 13-16 and contacts a specific target by the end of the process (Weavers and Skaer, 2013). It adopts a specialized morphology with the cell body projecting from the tubule tip on the end of a microtubule-enriched stalk (Weavers and Skaer, 2013). It can extend filopodia and lamellipodia to explore its environment and remains free of basement membrane (Weavers and Skaer, 2013).[ FlyBase:FBrf0223292 ]
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Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN       7
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       2
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN       5
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Relevant FlyBase reports
 Alleles Genes Insertions Constructs
 embryonic Malpighian tubule tip cell (all annotations which use CV term, excluding "NOT" statements)       7     18      2      5
     embryonic Malpighian tubule tip cell | ectopic       2       --       --       2
Spanning Tree (Parents/Children)
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specialized Malpighian tubule cell
 |__embryonic specialized Malpighian tubule cell__
 |__Malpighian tubule tip cell____________________|
ectodermal derivative                             |
 |__posterior ectoderm derivative_________________|
                                                  embryonic Malpighian tubule tip cell  32 rec.
                                                   |__embryonic anterior Malpighian tubule tip cell
                                                   |__embryonic posterior Malpighian tubule tip cell
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Is a embryonic specialized Malpighian tubule cell
Malpighian tubule tip cell
posterior ectoderm derivative
Develops from Malpighian tubule tip cell primordium
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