FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term adult Malpighian tubule principal cell ID (Ontology) FBbt:00005735 (Fly Anatomy)
Definition Type I (principal) cell of the adult Malpighian tubule. These are found throughout the tubule and outnumber other cell types overall (Singh et al., 2007). They transport cations and organic solutes (Singh et al., 2007).[ FlyBase:FBrf0202697 FlyBase:FBrf0245230 ]
Also Known As "adult Malpighian tubule primary cell" ; "adult Malpighian tubule Type I cell" ; "adult PC"
Comment It can be distinguished from other tubule cells by its high expression of cut, but stem cells also express a low level of cut (Wang and Spradling, 2020).
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Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN       5
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       4
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN       3
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Relevant FlyBase reports
 Alleles Genes  Insertions Constructs
 adult Malpighian tubule principal cell (all annotations which use CV term, excluding "NOT" statements)       6     12     11      4      6
     adult Malpighian tubule principal cell | ectopic | somatic clone       2       --       --       --       1
     adult Malpighian tubule principal cell | pharate adult stage       2       --       --       --       1
Spanning Tree (Parents/Children)
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specialized Malpighian tubule cell
 |__adult specialized Malpighian tubule cell__
 |__Malpighian tubule Type I cell_____________|
                                              adult Malpighian tubule principal cell  68 rec.
                                               |__adult Malpighian tubule principal cell of stem cell zone 18 rec.
                                               |   |__adult Malpighian tubule principal cell of lower segment 9 rec.
                                               |   |__adult Malpighian tubule principal cell of lower ureter 9 rec.
                                               |   |__adult Malpighian tubule principal cell of upper ureter
                                               |__adult Malpighian tubule principal cell of upper tubule 13 rec.
                                                   |__adult Malpighian tubule principal cell of initial segment 10 rec.
                                                   |__adult Malpighian tubule principal cell of main segment 3 rec.
                                                   |__adult Malpighian tubule principal cell of transitional segment
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Is a adult specialized Malpighian tubule cell
Malpighian tubule Type I cell
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