FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term larval Eh neurosecretory neuron ID (Ontology) FBbt:00006028 (Fly Anatomy)
Definition Larval neuron that expresses eclosion hormone (Eh). There is one of these in each hemisphere, with its soma in the tritocerebrum (Horodyski et al., 1993; Siegmund and Korge, 2001). Branches extend anteriorly and posteriorly, spanning the entire length of the central nervous system (Horodyski et al., 1993; Siegmund and Korge, 2001). It synapses onto other ring gland projection neurons and neurons in the ventral nerve cord that may be involved in ecdysis motor programs (Huckesfeld et al., 2021). Another branch extends posteriorly, then anteriorly, and follows the nervus corporis cardiaci to the ring gland, where it has peptide release sites in the corpus cardiacum and the aorta (Siegmund and Korge, 2001; Huckesfeld et al., 2021). It releases Eh around the time of ecdysis (Horodyski et al., 1993).[ FlyBase:FBrf0058431 FlyBase:FBrf0098847 FlyBase:FBrf0134726 FlyBase:FBrf0249161 ]
Also Known As "larval eclosion hormone neurosecretory neuron" ; "larval Eh neuron" ; "larval l-NSC EH" (for all, see Synonyms field below)
Comment McKim et al. (2024) - doi:10.7554/eLife.102684.1 class this as lateral.
Links to External Ontologies
VFB:FBbt_00006028
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN       2
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION      20
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN       2
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 Full annotation statements 
Relevant FlyBase reports
 Alleles Insertions Constructs
 larval Eh neurosecretory neuron (all annotations which use CV term, excluding "NOT" statements)       6     20      4
Spanning Tree (Parents/Children)
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larval neuron
 |__embryonic/larval corpus cardiacum innervating neuron__
peptidergic neuron                                        |
 |__eclosion hormone neuron_______________________________|
endocrine neuron                                          |
 |__eclosion hormone neuron_______________________________|
larval descending neuron                                  |
 |__larval descending neuron to VNC_______________________|
efferent neuron                                           |
 |__larval efferent neuron________________________________|
larval neurosecretory neuron                              |
 |__neurosecretory cell of larval brain___________________|
neurosecretory cell of brain                              |
 |__neurosecretory cell of larval brain___________________|
larval peptidergic neuron                                 |
 |__larval ring gland projection neuron___________________|
larval CNS neuron                                         |
 |__larval efferent neuron________________________________|
 |__neurosecretory cell of larval brain___________________|
                                                          larval Eh neurosecretory neuron  30 rec.
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Is a embryonic/larval corpus cardiacum innervating neuron
eclosion hormone neuron
larval descending neuron to VNC
larval efferent neuron
larval ring gland projection neuron
neurosecretory cell of larval brain
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Synonyms
Secondary IDs
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VFB:FBbt_00006028