FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term intestinal stem cell ID (Ontology) FBbt:00007039 (Fly Anatomy)
Definition Wedge shaped diploid cell found in scattered clusters in the midgut epithelium. The broad end of the wedge lies on the basement membrane and contains the nucleus. The tapering apex of the cell extends up towards the lumen.[ FlyBase:FBrf0007735 FlyBase:FBrf0191251 FlyBase:FBrf0227510 ]
Also Known As "ISC"
Comment Can be identified by expression of Delta (and escargot) (Zeng and Hou, 2015).
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Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN     246
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION      11
Insertions (FBti)  PHENOTYPE_MANIFEST_IN      20
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN     161
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes  Insertions Constructs
 intestinal stem cell (all annotations which use CV term, excluding "NOT" statements)     248     18     17     31    167
     intestinal stem cell | adult stage      73       --       --       4     55
     intestinal stem cell | adult stage | cell non-autonomous       3       --       --       --       2
     intestinal stem cell | adult stage | cell non-autonomous | increased number       2       --       --       --       --
     intestinal stem cell | adult stage | chemical conditional       3       --       --       --       3
     intestinal stem cell | adult stage | decreased number       5       --       --       --       2
     intestinal stem cell | adult stage | decreased number | somatic clone       4       --       --       --       4
     intestinal stem cell | adult stage | increased number      32       --       --       1     25
     intestinal stem cell | adult stage | nutrition conditional       2       --       --       --       1
     intestinal stem cell | adult stage | somatic clone      37       --       --       --      24
     intestinal stem cell | chemical conditional       9       --       --       --       7
     intestinal stem cell | decreased number       6       --       --       --       5
     intestinal stem cell | decreased number | conditional       4       --       --       --       2
     intestinal stem cell | decreased number | somatic clone       2       --       --       --       2
     intestinal stem cell | increased number       8       --       --       1      5
     intestinal stem cell | increased number | heat sensitive       3       --       --       --       2
     intestinal stem cell | increased number | somatic clone       1       --       --       --       --
     intestinal stem cell | late third instar larval stage | somatic clone       2       --       --       --       2
     intestinal stem cell | male | progressive       2       --       --       --       1
     intestinal stem cell | P-stage | increased number       4       --       --       --       3
     intestinal stem cell | prepupal stage | somatic clone       2       --       --       --       2
     intestinal stem cell | progressive       1       --       --       --       --
     intestinal stem cell | pupal stage | somatic clone       2       --       --       --       2
     intestinal stem cell | RU486 conditional       2       --       --       --       1
     intestinal stem cell | somatic clone      41       --       --       6     14
     intestinal stem cell | somatic clone | increased number       8       --       --       --       4
     intestinal stem cell | somatic clone | increased number | heat sensitive       1       --       --       --       --
     intestinal stem cell | temperature conditional       3       --       --       --       2
Spanning Tree (Parents/Children)
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somatic precursor cell__
stem cell_______________|
                        somatic stem cell
                         |__intestinal stem cell  651 rec.
                             |__intestinal stem cell of posterior adult midgut epithelium 217 rec.
                                 |__intestinal stem cell of the adult midgut-hindgut boundary 14 rec.
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Is a somatic stem cell
Part of adult midgut epithelium
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