FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term adult ellipsoid body R-neuron ID (Ontology) FBbt:00007507 (Fly Anatomy)
Definition Ring neuron that develops from the DALv2 neuroblast during the larval stage (Lovick et al., 2017; Omoto et al., 2018; Bridi et al., 2019). Its small soma is located in a cluster just dorsolateral to the antennal lobe and ventrolateral to the lateral accessory lobe (LAL) (Hanesch et al., 1989). There are approximately 150 R-neurons per hemisphere, making them more abundant than the extrinsic ring neurons (Omoto et al., 2018). They have projections that extend dorsoposteriorly, branching off localized neurites with postsynaptic terminals into the bulb or, less frequently, the LAL (Young and Armstrong, 2010; Omoto et al., 2018). They enter the lateral ellipsoid fascicle, and via a circular process, terminate medially into the ellipsoid body (EB) (Omoto et al., 2018). In the EB, distal neurites of R-neurons either project centrifugally (inside-out) or centripetally (outside-in) (Omoto et al., 2018) and have presynaptic terminals there (Young and Armstrong, 2010). They are GABAergic (Bridi et al., 2019). All subtypes have functions in regulating sleep (Yan et al., 2023).[ FlyBase:FBrf0049409 FlyBase:FBrf0111476 FlyBase:FBrf0210154 FlyBase:FBrf0236656 FlyBase:FBrf0240929 FlyBase:FBrf0243005 FlyBase:FBrf0255642 ]
Also Known As "ER" ; "ER-neuron" ; "LTR-EB" (for all, see Synonyms field below)
Comment Sites inferred to be presynaptic by localization of fluorescently tagged synaptobrevin and to be postsynaptic by localization of fluorescently tagged DSCAM (Young and Armstrong, 2010).
Links to External Ontologies
VFB:FBbt_00007507
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN       3
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       8
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN       2
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Insertions Constructs
 adult ellipsoid body R-neuron (all annotations which use CV term, excluding "NOT" statements)       4      3      8      5
Spanning Tree (Parents/Children)
Only view relationship: 
neuron
 |__secondary neuron_______________________
GABAergic neuron                           |
 |__adult GABAergic neuron_________________|
large field neuron of the central complex  |
 |__adult ellipsoid body ring neuron_______|
adult neuron                               |
 |__adult GABAergic neuron_________________|
adult CNS neuron                           |
 |__adult EBa1 lineage neuron______________|
DALv2 lineage neuron                       |
 |__adult EBa1 lineage neuron______________|
                                           adult ellipsoid body R-neuron  132 rec.
                                            |__adult ellipsoid body ring neuron R1 28 rec.
                                            |__adult ellipsoid body ring neuron R2 36 rec.
                                            |__adult ellipsoid body ring neuron R3 53 rec.
                                            |   |__adult ellipsoid body ring neuron R3a 1 rec.
                                            |   |__adult ellipsoid body ring neuron R3d 9 rec.
                                            |   |__adult ellipsoid body ring neuron R3m 6 rec.
                                            |   |__adult ellipsoid body ring neuron R3p 1 rec.
                                            |   |__adult ellipsoid body ring neuron R3w
                                            |__adult ellipsoid body ring neuron R4 88 rec.
                                            |   |__adult ellipsoid body ring neuron R4d 20 rec.
                                            |   |__adult ellipsoid body ring neuron R4m 16 rec.
                                            |__adult ellipsoid body ring neuron R5 3 rec.
                                            |__adult ellipsoid body ring neuron R6
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Is a adult ellipsoid body ring neuron
secondary neuron
adult EBa1 lineage neuron
adult GABAergic neuron
Develops from larval ellipsoid body R-neuron precursor
Part of
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Synonyms
Secondary IDs
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VFB:FBbt_00007507