FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term descending neuron of the posterior brain DNp11 ID (Ontology) FBbt:00047644 (Fly Anatomy)
Definition Descending neuron belonging to the DNp group, having a cell body posterior to the inferior posterior slope (Matsuo et al., 2016; Namiki et al., 2018). The primary neurite extends anterodorsally and branches in the posterior region of the posterior ventrolateral protocerebrum, with one branch extending laterally to form postsynaptic terminals in the lobula (Matsuo et al., 2016). A ventral branch forms a dense dendritic arbor encompassing the ipsilateral antennal mechanosensory and motor center zone B, wedge, posterior lateral protocerebrum, and anterior and posterior ventrolateral protocerebrum, including the LC4 glomerulus and non-glomerular regions (Matsuo et al., 2016). A thin neurite projects medially and fasciculates with the great commissure, then turns ventrally and forms presynaptic terminals bilaterally in the saddle and posterior gnathal ganglion (Matsuo et al., 2016). Some individuals may have additional ipsilateral brain innervation (Matsuo et al., 2016). It descends on the contralateral side of the cervical connective, fasciculates with the median tract of the dorsal cervical fascicle and innervates the intermediate and lower tectulum, abdominal neuromere, and T1 and T2 leg neuropils (Namiki et al., 2018). There is one of these cells per hemisphere (Matsuo et al., 2016; Namiki et al., 2018). It receives looming stimulus input from posterior LC4 neurons and its activity results in a forwards leaning posture and forwards takeoff (Dombrovski et al., 2023).[ FlyBase:FBrf0230862 FlyBase:FBrf0239335 FlyBase:FBrf0255530 ]
Also Known As "AMMC-Db3" ; "antennal mechanosensory and motor center AMMC Db3 neuron" ; "DNp11" (for all, see Synonyms field below)
Comment Db3a,b,c subtypes from Matsuo et al. (2016) represent individual differences in Db3 (DNp11) neurons, rather than distinct types.
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VFB:FBbt_00047644
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Data Class Field Records
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       4
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 descending neuron of the posterior brain DNp11 (all annotations which use CV term, excluding "NOT" statements)       4      4      8
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projection neuron
 |__wedge projection neuron_______________________________________
adult descending neuron                                           |
 |__descending neuron of the posterior brain______________________|
visual projection neuron                                          |
 |__adult visual projection neuron________________________________|
adult interneuron                                                 |
 |__great commissural interneuron_________________________________|
 |__adult visual projection neuron________________________________|
 |__wedge projection neuron_______________________________________|
adult CNS neuron                                                  |
 |__descending neuron of the posterior brain______________________|
adult antennal mechanosensory and motor center projection neuron  |
 |__antennal mechanosensory and motor center B projection neuron__|
                                                                  descending neuron of the posterior brain DNp11  16 rec.
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Is a great commissural interneuron
descending neuron of the posterior brain
adult visual projection neuron
wedge projection neuron
antennal mechanosensory and motor center B projection neuron
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VFB:FBbt_00047644