FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term larval ipc-1 neuron ID (Ontology) FBbt:00047844 (Fly Anatomy)
Definition Ion transport peptide (ITP)-expressing neuron of the larval pars lateralis. Its axon projects to the ring gland and has peptide release sites in the corpus cardiacum and aorta (Dircksen et al., 2008; Huckesfeld et al., 2021). There is some heterogeneity among this population; some cells may cross the midline and some may have release sites in the corpus allatum or prothoracic gland (Dircksen et al., 2008). Dendrites extend ventrally, close to the midline, reaching the subesophageal zone (Dircksen et al., 2008; Huckesfeld et al., 2021). They express the neuropeptide Leucokinin and this can be detected in the corpus cardiacum terminals, although it is less apparent in the soma (de Haro et al., 2010).[ FlyBase:FBrf0204742 FlyBase:FBrf0209907 FlyBase:FBrf0211291 FlyBase:FBrf0238083 FlyBase:FBrf0249161 ]
Also Known As "CC-LP 1" ; "larval ALK neuron" ; "larval anterior leucokinin neuron" (for all, see Synonyms field below)
Comment Mapped to CC-LP 2 from Siegmund and Korge (2001) - FBrf0134726 in Huckesfeld et al. (2021) - FBrf0249161, but CC-LP 2 is a cluster of 3 corazonin-expressing cells, so this more likely to correspond to CC-LP 1 - https://orcid.org/0000-0002-1373-1705. Park et al. (2008) - FBrf0210278 identify 4 'DMS/ITP?' cells in the PL that may correspond to ipc-1; they also identify a single 'LK' neuron.
Links to External Ontologies
VFB:FBbt_00047844
Annotations
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Data Class Field Records
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       8
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 Genes Insertions Constructs
 larval ipc-1 neuron (all annotations which use CV term, excluding "NOT" statements)       1      8      2
Spanning Tree (Parents/Children)
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supraesophageal ganglion neuron
 |__larval neurosecretory cell of pars lateralis____________
larval neuron                                               |
 |__embryonic/larval corpus cardiacum innervating neuron____|
neurosecretory cell of pars lateralis                       |
 |__ipc-1 neuron____________________________________________|
 |__larval neurosecretory cell of pars lateralis____________|
primary neuron                                              |
 |__larval neurosecretory cell of pars lateralis____________|
ITP neuron                                                  |
 |__ipc-1 neuron____________________________________________|
larval descending neuron                                    |
 |__larval descending neuron to SEZ_________________________|
efferent neuron                                             |
 |__ipc-1 neuron____________________________________________|
larval efferent neuron                                      |
 |__larval neurosecretory cell of pars lateralis____________|
larval ring gland projection neuron                         |
 |__larval neurosecretory cell of pars lateralis____________|
larval neurosecretory neuron                                |
 |__larval Leucokinin neuron of the central nervous system__|
neurosecretory cell of larval brain                         |
 |__larval neurosecretory cell of pars lateralis____________|
larval peptidergic neuron                                   |
 |__larval Leucokinin neuron of the central nervous system__|
larval CNS neuron                                           |
 |__larval Leucokinin neuron of the central nervous system__|
Leucokinin neuron                                           |
 |__larval Leucokinin neuron of the central nervous system__|
                                                            larval ipc-1 neuron  11 rec.
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Is a embryonic/larval corpus cardiacum innervating neuron
ipc-1 neuron
larval descending neuron to SEZ
larval Leucokinin neuron of the central nervous system
larval neurosecretory cell of pars lateralis
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VFB:FBbt_00047844