FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term adult NPF D1 neuron (male) ID (Ontology) FBbt:00048118 (Fly Anatomy)
Definition Male-specific neuropeptide F-expressing neuron of the adult with a cell body in the anterior dorsal brain, ventral to the D2 neurons, dorsolateral to the antennal lobe (Lee et al., 2006; Liu et al., 2019). It arborizes extensively in the superior brain (Lee et al., 2006; Liu et al., 2019). Its peptide release sites are in the anterior medial brain and its release of NPF suppresses male courtship (Liu et al., 2019). There are approximately 3 of these cells per hemisphere and they also express the male isoform of fruitless (Lee et al., 2006; Liu et al., 2019).[ FlyBase:FBrf0194171 FlyBase:FBrf0243395 ]
Also Known As "adult NPFM neuron" ; "NPFD1"
Comment NPF D1 from Lee et al. (2006) judged to be equivalent to NPFM from Liu et al. (2019) on the basis of belonging to a male-specific anterior cluster of ~3 neurons per hemisphere dorsolateral to the antennal lobe, expressing NPF and fru, and having dorsal arborization.
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VFB:FBbt_00048118
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neuron
 |__fruitless expressing neuron__
adult neuron                     |
 |__adult CNS neuron_____________|
male-specific anatomical entity  |
 |__male-specific neuron_________|
sexually-dimorphic neuron        |
 |__male-specific neuron_________|
NPF neuron                       |
 |__adult NPF neuron_____________|
adult peptidergic neuron         |
 |__adult NPF neuron_____________|
CNS neuron                       |
 |__adult CNS neuron_____________|
                                 adult NPF D1 neuron (male)
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Is a fruitless expressing neuron
adult NPF neuron
male-specific neuron
adult CNS neuron
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VFB:FBbt_00048118