FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term vertical system twin neuron 2 ID (Ontology) FBbt:00048130 (Fly Anatomy)
Definition Lobula plate tangential neuron that resembles vertical system neuron 3, with a dorsal extension into lobula plate layer 1 (Boergens et al., 2018; Zhao et al., 2023). It receives input in around 80 columns of lobula plate layer 4 and around 50 columns of layer 1 (Nern et al., 2025). It remains ipsilateral and its main output region is the inferior posterior slope (Dorkenwald et al., 2024; Schlegel et al., 2024). It is predicted to be cholinergic (Eckstein et al., 2024; Nern et al., 2025). There are four of these cells on each side (Zhao et al., 2023; Nern et al., 2025).[ FlyBase:FBrf0240805 FlyBase:FBrf0259490 FlyBase:FBrf0260535 FlyBase:FBrf0260546 FlyBase:FBrf0262545 ]
Also Known As "vertical system-like neuron 2" ; "vertical system-like neuron 3" ; "VS twin 2" (for all, see Synonyms field below)
Comment VSlike 2/3 from Boergens et al. (2018) judged to correspond to VST2 from Zhao et al. (2023) based on LOP layer 1+4 innervation.
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VFB:FBbt_00048130
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lobula plate tangential neuron
 |__vertical system-like neuron_____
cholinergic neuron                  |
 |__adult cholinergic neuron________|
adult neuron                        |
 |__adult cholinergic neuron________|
visual system neuron                |
 |__vertical system-like neuron_____|
visual projection neuron            |
 |__adult visual projection neuron__|
adult interneuron                   |
 |__adult visual projection neuron__|
                                    vertical system twin neuron 2
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Is a vertical system-like neuron
adult visual projection neuron
adult cholinergic neuron
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VFB:FBbt_00048130