FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term medulla-lobula neuron 1 ID (Ontology) FBbt:00052137 (Fly Anatomy)
Definition Optic lobe neuron that has its soma in the anterior medulla cell body rind, multicolumnar dendritic innervation of the medulla, and an axon that reaches the anterior lobula without passing through the second optic chiasm (Kind et al., 2021). Its dendritic arborization spans approximately 20 optic columns, ramifying in layers M1-4 and M8 from vertical processes (Kind et al., 2021). It receives synaptic input from R8 photoreceptors, mainly in pale optic columns (Kind et al., 2021). Its axon leaves the distal medulla and travels anteriorly to reach layer 6 of the lobula, where it has postsynapses in a few columns (Kind et al., 2021; Nern et al., 2025). In a subpopulation of these cells its axon also innervates the central brain (Kind et al., 2021). It is predicted to be cholinergic (Eckstein et al., 2024; Nern et al., 2025). There are around 45 of these cells per optic lobe (Kind et al., 2021; Nern et al., 2025).[ FlyBase:FBrf0252485 FlyBase:FBrf0259490 FlyBase:FBrf0262545 ]
Also Known As "adult CB3833 neuron" ; "adult medulla-lobula neuron MeLo1" ; "adult ML1 neuron" (for all, see Synonyms field below)
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VFB:FBbt_00052137
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 medulla-lobula neuron 1 (all annotations which use CV term, excluding "NOT" statements)       1      2
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supraesophageal ganglion neuron
 |__adult optic lobe neuron________________
adult optic lobe columnar neuron           |
 |__optic lobe wide-field columnar neuron__|
cholinergic neuron                         |
 |__adult cholinergic neuron_______________|
sensory system neuron                      |
 |__visual system neuron___________________|
anterior ectoderm derivative               |
 |__adult optic lobe neuron________________|
adult neuron                               |
 |__adult cholinergic neuron_______________|
adult CNS neuron                           |
 |__adult optic lobe neuron________________|
                                           medulla-lobula neuron 1  3 rec.
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Is a adult optic lobe neuron
visual system neuron
adult cholinergic neuron
optic lobe wide-field columnar neuron
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VFB:FBbt_00052137