FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term large central-projecting DN3 neuron ID (Ontology) FBbt:00052758 (Fly Anatomy)
Definition Large DN3 neuron that projects centrally, crossing the midline (Sun et al., 2022). It receives most of its input in the ipsilateral posterior lateral protocerebrum, as well as the accessory medulla and lobula layer 1 (Dorkenwald et al., 2024; Schlegel et al., 2024; Nern et al., 2025). It sends output to the superior medial protocerebrum in both hemispheres, and the contralateral superior lateral protocerebrum (Dorkenwald et al., 2024; Schlegel et al., 2024). It also has pre-and post-synapses in the contralateral mushroom body calyx (Dorkenwald et al., 2024; Schlegel et al., 2024). There is one of these cells per hemisphere (Reinhard et al., 2022). It is cholinergic (Reinhard et al., 2024).[ FlyBase:FBrf0253505 FlyBase:FBrf0253946 FlyBase:FBrf0260535 FlyBase:FBrf0260546 FlyBase:FBrf0261099 FlyBase:FBrf0262545 ]
Also Known As "aMe13" ; "l-CPDN3"
Comment Mapped to aMe13 in FlyWire Codex.
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VFB:FBbt_00052758
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DN3 neuron
 |__large DN3 neuron_____________________________________
cholinergic neuron                                       |
 |__adult cholinergic neuron_____________________________|
adult neuron                                             |
 |__adult cholinergic neuron_____________________________|
adult visual projection neuron                           |
 |__adult visual projection neuron to the mushroom body__|
accessory medulla neuron                                 |
 |__large DN3 neuron_____________________________________|
mushroom body extrinsic neuron                           |
 |__adult visual projection neuron to the mushroom body__|
                                                         large central-projecting DN3 neuron
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Is a adult visual projection neuron to the mushroom body
large DN3 neuron
adult cholinergic neuron
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VFB:FBbt_00052758