General Information
Term	adult brake neuron	ID (Ontology)	FBbt:00053379 (Fly Anatomy)
Definition	Adult ascending neuron with its soma in a thoracic neuromere and an axonal projection to the subesophageal zone (Sapkal et al., 2024). It also outputs to the tectulum (Sapkal et al., 2024). There is one of these per thoracic hemineuromere. Its activation causes halting (Sapkal et al., 2024).[ FlyBase:FBrf0260559 ]
Also Known As	"BRK neuron"
Comment	Sapkal et al. (2024) show that this is excitatory, but do not confirm neurotransmitter. Subtype of AN19A018 based on body ids in Sapkal et al. (2024) supplement. AN19A018 also mapped to brake neurons in Bates et al. (2025) - doi:10.1101/2025.07.31.667571.
Links to External Ontologies
	VFB:FBbt_00053379
Annotations
Records annotated with this term OR any of its CHILD TERMS
No relevant records available
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available

General Information

Term

adult brake neuron

ID (Ontology)

FBbt:00053379 (Fly Anatomy)

Definition

Adult ascending neuron with its soma in a thoracic neuromere and an axonal projection to the subesophageal zone (Sapkal et al., 2024). It also outputs to the tectulum (Sapkal et al., 2024). There is one of these per thoracic hemineuromere. Its activation causes halting (Sapkal et al., 2024).[ FlyBase:FBrf0260559 ]

Also Known As

"BRK neuron"

Comment

Sapkal et al. (2024) show that this is excitatory, but do not confirm neurotransmitter. Subtype of AN19A018 based on body ids in Sapkal et al. (2024) supplement. AN19A018 also mapped to brake neurons in Bates et al. (2025) - doi:10.1101/2025.07.31.667571.

Links to External Ontologies

VFB:FBbt_00053379

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

neuron
 |__thoracic neuron_______________
adult ascending neuron            |
 |__adult AN19A018 neuron_________|
hemilineage 19A secondary neuron  |
 |__adult AN19A018 neuron_________|
adult cholinergic neuron          |
 |__adult AN19A018 neuron_________|
adult GABAergic neuron            |
 |__adult AN19A018 neuron_________|
adult CNS neuron                  |
 |__adult VNC neuron______________|
 |__adult AN19A018 neuron_________|
                                  adult brake neuron
                                   |__adult mesothoracic brake neuron
                                   |__adult metathoracic brake neuron
                                   |__adult prothoracic brake neuron

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	thoracic neuron adult VNC neuron adult AN19A018 neuron
Part of
Synonyms & Secondary IDs
Synonyms
	"AN_GNG_53" NARROW "AN_GNG_54" NARROW "AN_GNG_76" NARROW "BRK neuron" EXACT[ FlyBase:FBrf0260559 ]
Secondary IDs

External Crossreferences & Linkouts
	VFB:FBbt_00053379

Spanning Tree View Settings

Parents/Children
View Depth

Relationships

Is a

thoracic neuron
adult VNC neuron
adult AN19A018 neuron

Part of

Synonyms & Secondary IDs

Synonyms

"AN_GNG_53" NARROW
"AN_GNG_54" NARROW
"AN_GNG_76" NARROW
"BRK neuron" EXACT[ FlyBase:FBrf0260559 ]

Secondary IDs

External Crossreferences & Linkouts

VFB:FBbt_00053379