FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term adult medulla-lobula neuron MeLo3b ID (Ontology) FBbt:00053503 (Fly Anatomy)
Definition Adult unilateral optic-lobe-intrinsic neuron with its soma on the dorsal side of the medulla (Dorkenwald et al., 2024; Schlegel et al., 2024; Nern et al., 2025). It bifurcates near the soma, sending one branch to the medulla and one to the lobula, without passing through the optic chiasm (Nern et al., 2025). It receives input, but also has presynapses, in medulla layers M3-M4 and M6-M7 in around 10 columns (Nern et al., 2025). It also has pre- and post-synapses in the lobula, in around 10 columns of layer 6 (Nern et al., 2025). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024; Nern et al., 2025). There are approximately 40 of these cells per hemisphere (Nern et al., 2025).[ FlyBase:FBrf0259490 FlyBase:FBrf0260535 FlyBase:FBrf0260545 FlyBase:FBrf0260546 FlyBase:FBrf0262545 ]
Also Known As "MeLo3b" ; "MLt5"
Comment Cell type identified in two sets of EM data (Matsliah et al., 2024; Nern et al., 2024), matched and identified at light level by Nern et al. (2025).
Links to External Ontologies
VFB:FBbt_00053503
Annotations
Records annotated with this term OR any of its CHILD TERMS
No relevant records available
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available
Spanning Tree (Parents/Children)
Only view relationship:
supraesophageal ganglion neuron
 |__adult optic lobe neuron_____________
cholinergic neuron                      |
 |__adult cholinergic neuron____________|
anterior ectoderm derivative            |
 |__adult optic lobe neuron_____________|
adult neuron                            |
 |__adult cholinergic neuron____________|
adult interneuron                       |
 |__medulla-lobula connecting neuron____|
adult visual neuropil intrinsic neuron  |
 |__adult optic lobe intrinsic neuron___|
adult CNS neuron                        |
 |__adult optic lobe neuron_____________|
                                        adult medulla-lobula neuron MeLo3b
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a adult optic lobe neuron
adult optic lobe intrinsic neuron
medulla-lobula connecting neuron
adult cholinergic neuron
Part of
hide Synonyms & Secondary IDs
Synonyms
Secondary IDs
hide External Crossreferences & Linkouts
VFB:FBbt_00053503