General Information
Term	larval Akh secreting cell	ID (Ontology)	FBbt:00058018 (Fly Anatomy)
Definition	Peptidergic neuron that secretes the glucagon-like Adipokinetic hormone (Akh). This includes all and only the cells of the larval corpus cardiacum (Lee and Park, 2004; Park et al., 2008). They have projections to the prothoracic gland and the aorta, where they have peptide-release sites (Lee and Park, 2004; Hughson et al., 2021). They can store insulin like peptides released by the insulin secreting cells of the pars intercerebralis and release these, along with Akh, to the prothoracic gland (Ghosh et al., 2022). They are involved in regulating larval developmental rate in low-nutrient conditions (Hughson et al., 2021; Ghosh et al., 2022). Each corpus cardiacum lobe contains approximately 7-8 of these cells (Lee and Park, 2004; Park et al., 2008).[ FlyBase:FBrf0178933 FlyBase:FBrf0210278 FlyBase:FBrf0248385 FlyBase:FBrf0253296 ]
Also Known As	"larval Akh neuron"
Comment	Expresses synaptobrevin and described as having 'axonal projections' (Hughson et al., 2021), therefore classified as a neuron.
Links to External Ontologies
	VFB:FBbt_00058018
Annotations
Records annotated with this term OR any of its CHILD TERMS
No relevant records available
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available

General Information

Term

larval Akh secreting cell

ID (Ontology)

FBbt:00058018 (Fly Anatomy)

Definition

Peptidergic neuron that secretes the glucagon-like Adipokinetic hormone (Akh). This includes all and only the cells of the larval corpus cardiacum (Lee and Park, 2004; Park et al., 2008). They have projections to the prothoracic gland and the aorta, where they have peptide-release sites (Lee and Park, 2004; Hughson et al., 2021). They can store insulin like peptides released by the insulin secreting cells of the pars intercerebralis and release these, along with Akh, to the prothoracic gland (Ghosh et al., 2022). They are involved in regulating larval developmental rate in low-nutrient conditions (Hughson et al., 2021; Ghosh et al., 2022). Each corpus cardiacum lobe contains approximately 7-8 of these cells (Lee and Park, 2004; Park et al., 2008).[ FlyBase:FBrf0178933 FlyBase:FBrf0210278 FlyBase:FBrf0248385 FlyBase:FBrf0253296 ]

Also Known As

"larval Akh neuron"

Comment

Expresses synaptobrevin and described as having 'axonal projections' (Hughson et al., 2021), therefore classified as a neuron.

Links to External Ontologies

VFB:FBbt_00058018

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

larval neuron
 |__prothoracic gland innervating neuron__________________
 |__embryonic/larval corpus cardiacum innervating neuron__|
 |__larval neurosecretory neuron__________________________|
 |__larval peptidergic neuron_____________________________|
peptidergic neuron                                        |
 |__larval peptidergic neuron_____________________________|
neurosecretory neuron                                     |
 |__larval neurosecretory neuron__________________________|
endocrine neuron                                          |
 |__Akh secreting cell____________________________________|
endocrine cell of the ring gland                          |
 |__Akh secreting cell____________________________________|
 |__endocrine cell of the larval ring gland_______________|
                                                          larval Akh secreting cell

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Is a	prothoracic gland innervating neuron embryonic/larval corpus cardiacum innervating neuron larval neurosecretory neuron Akh secreting cell larval peptidergic neuron endocrine cell of the larval ring gland
Part of
Synonyms & Secondary IDs
Synonyms
	"larval Akh neuron" EXACT
Secondary IDs

External Crossreferences & Linkouts
	VFB:FBbt_00058018

Spanning Tree View Settings

Parents/Children
View Depth

Relationships

Is a

prothoracic gland innervating neuron
embryonic/larval corpus cardiacum innervating neuron
larval neurosecretory neuron
Akh secreting cell
larval peptidergic neuron
endocrine cell of the larval ring gland

Part of

Synonyms & Secondary IDs

Synonyms

"larval Akh neuron" EXACT

Secondary IDs

External Crossreferences & Linkouts

VFB:FBbt_00058018