FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term mushroom body medial-vertical lobe arborizing neuron 1 ID (Ontology) FBbt:00100241 (Fly Anatomy)
Definition A neuron whose cell body is located in the inferior neuropils, lateral to the mushroom body calyx (Tanaka et al., 2008), in the dopaminergic PPL1 cluster (Aso et al., 2014). The cell body fiber projects towards the anterior of the inferior neuropils and on the way there it bifurcates with one branch turning ventrally and terminating in the ventral complex (Tanaka et al., 2008). The second branch further branches in the crepine close to the beta lobe (Tanaka et al., 2008), with dendritic arborization (Aso et al., 2020). One fiber runs medially to the opposite hemisphere (Tanaka et al., 2008). Another turns ventrolaterally and arborizes in the basal segments of the gamma lobe (slice 2) and alpha' lobe (slice 1) (Tanaka et al., 2008; Li et al., 2020). The contralateral fiber innervates the same mushroom body regions (Li et al., 2020). The final branch arborizes in the superior medial protocerebrum (Tanaka et al., 2008), with dendritic arborization (Aso et al., 2014). There is one neuron of this type in each hemisphere (Aso et al., 2014; Li et al., 2020) and it develops from the larval DAN-d1 (Truman et al., 2023). It is involved in aversive learning and forgetting (Berry et al., 2018).[ FlyBase:FBrf0205263 FlyBase:FBrf0227179 FlyBase:FBrf0240372 FlyBase:FBrf0248215 FlyBase:FBrf0255928 ]
Also Known As "DAN-gamma2alpha'1" ; "MB-MV1" ; "MZ604 (1)" (for all, see Synonyms field below)
Comment Names are assigned according to the area of the mushroom body they arborize, as detailed in Tanaka et al. (2008). The PPL1 cluster was identified by TH immunostaining and using a TH-GAL4 driver (FBtp0020119) (Liu et al., 2012).
Links to External Ontologies
VFB:FBbt_00100241
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Data Class Field Records
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       5
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 mushroom body medial-vertical lobe arborizing neuron 1 (all annotations which use CV term, excluding "NOT" statements)       1     33      5     35
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neuron
 |__primary neuron_________________
mushroom body dopaminergic neuron  |
 |__mushroom body PPL1 neuron______|
adult CNS neuron                   |
 |__adult DL2 lineage neuron_______|
dopaminergic PPL1 neuron           |
 |__mushroom body PPL1 neuron______|
CP3 lineage neuron                 |
 |__adult DL2 lineage neuron_______|
                                   mushroom body medial-vertical lobe arborizing neuron 1  74 rec.
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Is a primary neuron
mushroom body PPL1 neuron
adult DL2 lineage neuron
Develops from larval mushroom body dopaminergic neuron d1
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FlyBrain_NDB:10466
VFB:FBbt_00100241