FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term mushroom body output neuron 18 ID (Ontology) FBbt:00110101 (Fly Anatomy)
Definition A mushroom body ventral lobe arborizing neuron 2 that innervates across the shaft of the alpha lobe (slice 2) in the surface and core layers of the ipsilateral mushroom body and projects bilaterally to the superior intermediate protocerebrum, superior lateral protocerebrum and dorsal lateral horn. There is one neuron of this type in each hemisphere (Aso et al., 2014; Li et al., 2020; Truman et al., 2023) and it is a DL1 (CP2) secondary neuron (Truman et al., 2023). It outputs onto the lateral horn output neurons PD2a1 and PD2b1 (Dolan et al., 2018). It is involved in food odor attraction (Sayin et al., 2019), as well as short and medium term aversive memory (Bouzaiane et al., 2015).[ FlyBase:FBrf0214029 FlyBase:FBrf0227179 FlyBase:FBrf0228475 FlyBase:FBrf0240600 FlyBase:FBrf0243986 FlyBase:FBrf0248215 FlyBase:FBrf0255928 ]
Also Known As "MB-V2 alpha neuron" ; "MBON-18" ; "MBON-alpha2sc" (for all, see Synonyms field below)
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VFB:FBbt_00110101
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Data Class Field Records
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       1
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Relevant FlyBase reports
 Alleles  Insertions Constructs
 mushroom body output neuron 18 (all annotations which use CV term, excluding "NOT" statements)       1      5      1     12
Spanning Tree (Parents/Children)
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supraesophageal ganglion neuron
 |__mushroom body vertical lobe arborizing neuron 2__
neuron                                               |
 |__secondary neuron_________________________________|
adult mushroom body output neuron                    |
 |__adult typical mushroom body output neuron________|
adult lateral horn input neuron                      |
 |__mushroom body vertical lobe arborizing neuron 2__|
adult cholinergic neuron                             |
 |__mushroom body vertical lobe arborizing neuron 2__|
adult CNS neuron                                     |
 |__adult DL1 lineage neuron_________________________|
mushroom body extrinsic neuron                       |
 |__mushroom body vertical lobe arborizing neuron 2__|
CP2 lineage neuron                                   |
 |__adult DL1 lineage neuron_________________________|
                                                     mushroom body output neuron 18  19 rec.
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Is a secondary neuron
adult typical mushroom body output neuron
adult DL1 lineage neuron
mushroom body vertical lobe arborizing neuron 2
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VFB:FBbt_00110101