FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term antennal mechanosensory and motor center A2 projection neuron ID (Ontology) FBbt:00110124 (Fly Anatomy)
Definition Auditory projection neuron whose cell body is located on the ventrolateral side of the antennal lobe (Matsuo et al., 2016). Its cell body fiber extends medioventrally, bifurcating close to the midline and sending branches bilaterally into the inferior AMMC commissure (Lai et al., 2012; Matsuo et al., 2016). It has dendrites in AMMC zones A and B in both hemispheres and axonal terminals in the ipsilateral wedge (Lai et al., 2012; Matsuo et al., 2016). These neurons are broadly tuned to respond to 100 Hz, 300 Hz, 700 Hz or pulse song stimuli (Lai et al., 2012), with a greater response to pulse song (Baker et al., 2022). There are one or more of these cells per hemisphere (Matsuo et al., 2016) and they are cholinergic (Baker et al., 2022).[ FlyBase:FBrf0217491 FlyBase:FBrf0230862 FlyBase:FBrf0254226 ]
Also Known As "AMMC-A2" ; "AMMC-A2 neuron" ; "AMMC-A2 PN"
Comment Auditory function was determined measuring GCaMP activation in these cells in response to an acoustic stimuli in a subset of neurons labeled with VT30609-GAL4. This driver also labels AMMC-B1b neurons, although these two types can be distinguished by its acoustic response: only AMMC-A2 neurons respond to 700 Hz stimuli. Presence of pre- and postsynaptic sites was determined by immunoreactivity to Dscam- and synaptotagmin-GFP localization, respectively (Lai et al., 2012). Neurotransmitter predicted from EM data (Baker et al., 2022).
Links to External Ontologies
VFB:FBbt_00110124
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 antennal mechanosensory and motor center A2 projection neuron (all annotations which use CV term, excluding "NOT" statements)       1
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cholinergic neuron
 |__adult cholinergic neuron______________________________________
mechanosensory system neuron                                      |
 |__auditory system neuron________________________________________|
adult neuron                                                      |
 |__adult cholinergic neuron______________________________________|
adult interneuron                                                 |
 |__adult mechanosensory projection neuron________________________|
mechanosensory projection neuron                                  |
 |__adult mechanosensory projection neuron________________________|
CNS neuron                                                        |
 |__supraesophageal ganglion neuron_______________________________|
adult antennal mechanosensory and motor center projection neuron  |
 |__antennal mechanosensory and motor center B projection neuron__|
 |__antennal mechanosensory and motor center A projection neuron__|
                                                                  antennal mechanosensory and motor center A2 projection neuron  1 rec.
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Is a supraesophageal ganglion neuron
adult mechanosensory projection neuron
adult cholinergic neuron
antennal mechanosensory and motor center B projection neuron
antennal mechanosensory and motor center A projection neuron
auditory system neuron
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VFB:FBbt_00110124