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General Information
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| Term |
adult dopaminergic VUM neuron of the gnathal ganglion |
ID (Ontology) |
FBbt:00110128 (Fly Anatomy) |
| Definition |
Unpaired adult dopaminergic intrinsic gnathal ganglion neuron whose cell body is located ventromedially in the gnathal ganglion (Marella et al., 2012; Sterne et al., 2021). It arborizes extensively in the ventroanterior area of the gnathal ganglion with presynaptic and postsynaptic terminals (Marella et al., 2012; Sterne et al., 2021). It is involved in modulating the proboscis extension response (PER) with its activity being sufficient to trigger PER (Marella et al., 2012).[ FlyBase:FBrf0217751 FlyBase:FBrf0251280 ] |
| Also Known As |
"adult dopaminergic SB VUM neuron" ; "adult subesophageal ventral unpaired median dopaminergic neuron" ; "TH-VUM" (for all, see Synonyms field below) |
| Comment |
The nature of the neurotransmitter was assessed by labelling cells with a tyrosine hydroxylase GAL4 driver (TH-GAL4 - FBtp0020119) and by using an antibody against tyrosine hydroxylase. Presynaptic terminals were labeled with synaptobrevin-GFP. Specific activation of the VUM neuron with UAS-TRPA1 (FBtp0040248) triggers proboscis extension. The tonic firing rate of the VUM neuron is low in conditions when the probability of proboscis extension is low (satiety) and increases in conditions when the probability of extension is high (hunger) (Marella et al., 2012). |
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Links to External Ontologies
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VFB:FBbt_00110128
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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No relevant records available
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| | Constructs |
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adult dopaminergic VUM neuron of the gnathal ganglion (all annotations which use CV term, excluding "NOT" statements) | 7 | 16 |
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Relationships