FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term octopaminergic VPM2 neuron ID (Ontology) FBbt:00110150 (Fly Anatomy)
Definition Octopaminergic descending neuron whose cell body is located slightly lateral to the subesophageal ganglion midline, in the mandibular segment (Busch et al., 2009; Schlegel et al., 2024; Dorkenwald et al., 2024). Its main neurite projects to the area surrounding the ventral esophagus foramen where it crosses the midline and bifurcates at the ventral part of the contralateral ventrolateral protocerebrum (Busch et al., 2009). These processes innervate the contralateral ventrolateral, ventromedial, anterior inferior medial protocerebra and the subesophageal ganglion (Busch et al., 2009). There is also some innervation in the ipsilateral subesophageal ganglion (Busch et al., 2009). In the VNC, it follows the dorsal lateral tract of ventral cervical fasciculus (Sturner et al., 2024). There are 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2024).[ FlyBase:FBrf0207458 FlyBase:FBrf0210649 FlyBase:FBrf0212145 FlyBase:FBrf0260535 FlyBase:FBrf0260546 ]
Also Known As "descending neuron of the gnathal ganglion DNg104" ; "DNxn072" ; "OA-VPM2" (for all, see Synonyms field below)
Comment The neurotransmitter was assessed by immunostaining with an anti-octopamine (OA) antibody in cells labelled with tdc2-GAL4 (FBti0101786) and NP7088-GAL4 (FBti0037217) (Busch et al., 2009) or only using the tdc2-GAL4 (FBti0101786) (Busch and Tanimoto, 2010). Certel et al. (2010) describes a OA-VPM2 neuron, although it resembles the VMP1 subtype, and not the VPM2 described by Busch et al. (2009). Pre- or post-synapse locations are those with the highest total count of these neurons in FlyWire FAFB.
Links to External Ontologies
VFB:FBbt_00110150
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adult descending neuron
 |__descending neuron of the gnathal ganglion______
gnathal ganglion neuron                            |
 |__descending neuron of the gnathal ganglion______|
adult interneuron                                  |
 |__adult subesophageal zone output neuron_________|
input/output neuron                                |
 |__adult subesophageal zone output neuron_________|
adult CNS neuron                                   |
 |__descending neuron of the gnathal ganglion______|
adult octopaminergic subesophageal VM neuron       |
 |__adult mandibular octopaminergic VM neuron______|
 |__adult octopaminergic subesophageal VPM neuron__|
                                                   octopaminergic VPM2 neuron
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Is a descending neuron of the gnathal ganglion
adult subesophageal zone output neuron
adult mandibular octopaminergic VM neuron
adult octopaminergic subesophageal VPM neuron
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Synonyms
  • "descending neuron of the gnathal ganglion DNg104" EXACT
    "DNxn072" EXACT
    "OA-VPM2" EXACT VFB_SYMBOL[ FlyBase:FBrf0207458 ]
    "ventral paired median octopaminergic neuron 2" EXACT
Secondary IDs
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VFB:FBbt_00110150