FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term enteroblast ID (Ontology) FBbt:00110205 (Fly Anatomy)
Definition Non-proliferative cell that arises from the division of an intestinal stem cell in the adult midgut and is committed to differentiate into an enterocyte (Zeng and Hou, 2015; He et al., 2018; Reiff et al., 2019).[ FlyBase:FBrf0191251 FlyBase:FBrf0227510 FlyBase:FBrf0238268 FlyBase:FBrf0243895 ]
Also Known As "EB" ; "enterocyte-committed progenitor cell" ; "Notch-active enterocyte progenitor"
Comment These cells can be identified by their expression of a Su(H)GBE reporter, indicating active Notch signaling (He et al., 2018; Reiff et al., 2019). Cells expressing this reporter do not differentiate into enteroendocrine cells under normal conditions (Zeng and Hou, 2015). They also express klumpfuss (Reiff et al., 2019).
Links to External Ontologies
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN      94
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION      12
Insertions (FBti)  PHENOTYPE_MANIFEST_IN       6
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN      60
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes  Insertions Constructs
 enteroblast (all annotations which use CV term, excluding "NOT" statements)      97     11     17     18     66
     enteroblast | adult stage      38       --       --       4     24
     enteroblast | adult stage | cell non-autonomous       3       --       --       --       2
     enteroblast | adult stage | cell non-autonomous | increased number       2       --       --       --       --
     enteroblast | adult stage | decreased number       4       --       --       --       2
     enteroblast | adult stage | decreased number | somatic clone       2       --       --       --       2
     enteroblast | adult stage | increased number      34       --       --       1     17
     enteroblast | decreased number       3       --       --       --       2
     enteroblast | increased number       7       --       --       --       6
     enteroblast | progressive       1       --       --       --       --
     enteroblast | somatic clone       3       --       --       --       1
     enteroblast | third instar larval stage       3       --       --       --       2
Spanning Tree (Parents/Children)
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developing material anatomical entity__
somatic cell___________________________|
                                       somatic precursor cell
                                        |__enteroblast  266 rec.
                                            |__enteroblast of posterior adult midgut epithelium 68 rec.
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Is a somatic precursor cell
Develops from intestinal stem cell
Part of adult midgut epithelium
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