|
General Information
|
| Term |
adult fruitless P1 (male) neuron |
ID (Ontology) |
FBbt:00110621 (Fly Anatomy) |
| Definition |
Male-specific fruitless neuron with its soma in the dorsal posterior brain, mediolateral to the mushroom body (Kimura et al., 2008). It develops from the DM4 neuroblast (Ren et al., 2016). It extends a primary neurite anterodorsally, which ramifies extensively toward the lateral and medial protocerebrum regions (Kimura et al., 2008). A long prominent neurite crosses the midline through the anterior superior medial protocerebrum, ending at the corresponding contralateral region (Kimura et al., 2008). It has presynaptic sites in the protocerebral bridge (Duhart et al., 2020). These neurons are a subset of the doublesex pC1 neurons (Zhou et al., 2015). It is involved in the decision to initiate courtship song, including pulse and sine song (Philipsborn et al., 2011; O'Sullivan et al., 2018). Its activity can also suppress sleep (Duhart et al., 2020). It expresses the insulin receptor (InR) and is suppressed by insulin from the insulin producing cells of the pars intercerebralis (Zhang et al., 2022). There are approximately 50 of these cells per hemisphere (Ren et al., 2016).[ FlyBase:FBrf0128543 FlyBase:FBrf0205974 FlyBase:FBrf0211884 FlyBase:FBrf0211926 FlyBase:FBrf0212984 FlyBase:FBrf0229653 FlyBase:FBrf0233706 FlyBase:FBrf0240039 FlyBase:FBrf0247138 FlyBase:FBrf0252940 ] |
| Also Known As |
"adult fruitless pMP-e (male) neuron" ; "adult male fruitless pMP-e neuron" ; "adult male fruitless pMP4 neuron" (for all, see Synonyms field below) |
| Comment |
pC1 has been listed as an exact synonym for this in the past, but pC1 is actually a type of doublesex-expressing neuron (Rideout et al., 2010 - FBrf0210397), which now has its own class - FBbt:00047348. pMP-e (P1) is a subset of pC1 (Zhou et al., 2015). |
|
Links to External Ontologies
|
|
VFB:FBbt_00110621
|
|
Annotations
|
|
Records annotated with this term OR any of its CHILD TERMS
|
|
|
|
Records annotated with this exact term (annotations to child terms are NOT included)
|
| Data Class | Field | Records |
|---|
|
| Alleles (FBal) | PHENOTYPE_MANIFEST_IN | 8 | | Insertions (FBti) | EXPRESSION_STAGE_TISSUE_POSITION | 8 | | Insertions (FBti) | PHENOTYPE_MANIFEST_IN | 2 | | Constructs (FBtp) | PHENOTYPE_MANIFEST_IN | 8 |
|
Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
|
| Full annotation statements | Relevant FlyBase reports |
|---|
| Alleles | | Genes | Insertions | Constructs |
|---|
adult fruitless P1 (male) neuron (all annotations which use CV term, excluding "NOT" statements) | 9 | 8 | 2 | 12 | 22 | adult fruitless P1 (male) neuron | conditional | 2 | -- | -- | -- | 2 | adult fruitless P1 (male) neuron | decreased number | 6 | -- | -- | 2 | 6 |
|
Relationships