FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term mushroom body output neuron 12 ID (Ontology) FBbt:00111009 (Fly Anatomy)
Definition A cholinergic neuron whose dendrites arborize in gamma lobe slice 2 and alpha' lobe slice 1 with axonal terminals found in the crepine and superior medial protocerebrum (Aso et al., 2014). There are 2 neurons of this type in each hemisphere (Aso et al., 2014; Li et al., 2020; Truman et al., 2023) and they are secondary FLAa2 (BAmas1) neurons (Truman et al., 2023). It is involved in multiple stages of reward and punishment memory (Yamazaki et al., 2018; Ichinose et al., 2021) and promotes post-learning sleep (Lei et al., 2022).[ FlyBase:FBrf0227179 FlyBase:FBrf0238232 FlyBase:FBrf0248215 FlyBase:FBrf0248476 FlyBase:FBrf0252547 FlyBase:FBrf0255928 ]
Also Known As "MBON-12" ; "MBON-gamma2alpha'1" ; "MBON12"
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VFB:FBbt_00111009
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 mushroom body output neuron 12 (all annotations which use CV term, excluding "NOT" statements)       3     11
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neuron
 |__secondary neuron___________________________
cholinergic neuron                             |
 |__adult cholinergic neuron___________________|
adult neuron                                   |
 |__adult cholinergic neuron___________________|
adult mushroom body output neuron              |
 |__adult typical mushroom body output neuron__|
CNS neuron                                     |
 |__supraesophageal ganglion neuron____________|
adult CNS neuron                               |
 |__adult FLAa2 lineage neuron_________________|
BAmas1 lineage neuron                          |
 |__adult FLAa2 lineage neuron_________________|
                                               mushroom body output neuron 12  14 rec.
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Is a supraesophageal ganglion neuron
secondary neuron
adult typical mushroom body output neuron
adult FLAa2 lineage neuron
adult cholinergic neuron
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VFB:FBbt_00111009