FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term larval Jaam3 neuron ID (Ontology) FBbt:00111658 (Fly Anatomy)
Definition Interneuron of the larval ventral nerve cord (Heckscher et al., 2015) that is late-born in the NB5-2 Notch OFF primary hemilineage (Mark et al., 2021). The primary neurite extends into the neuropil forming one arbor that extends anteriorly (Heckscher et al., 2015). One neurite crosses the midline and forms a broad arbor that extends anteriolaterally and overlaps with the dendrites of the A08e1 local neuron, to which it outputs (Heckscher et al., 2015). It also forms substantial synapses to Jaam1 (Heckscher et al., 2015). It receives strong input from dorsal proprioceptive multidendritic neurons and the dorsal bipolar neuron (dbp) (Heckscher et al., 2015). There is one of these neuron per hemineuromere (Heckscher et al., 2015).[ FlyBase:FBrf0229965 FlyBase:FBrf0249021 ]
Also Known As "A06j"
Comment These neurons were identified in two EM reconstructions: one of the full CNS of a 6h old first instar larva, and another of abdominal segment 3 of a 12-24h old first instar larva. Only bilateral connections are reported. The number of identified input synapses in A1 was the following (number in brackets left/right): from dbp (9/11), from ddaD/ddaE/dda1 (35/40). The number of identified output synapses was the following (number in brackets left/right): to Jaam1 (19/18), to A08e1 (12/18). It is still not known if the pattern of connections is the same in the other abdominal segments (Heckscher et al., 2015). HMD3 and A12c3 synonyms from catmaid.
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VFB:FBbt_00111658
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interneuron
 |__larval interneuron__________________________
sensory system neuron                           |
 |__proprioceptive system neuron________________|
Notch OFF hemilineage primary neuron            |
 |__NB5-2 Notch OFF hemilineage primary neuron__|
NB5-2 lineage primary neuron                    |
 |__lineage NB5-2 primary interneuron___________|
 |__NB5-2 Notch OFF hemilineage primary neuron__|
primary interneuron                             |
 |__lineage NB5-2 primary interneuron___________|
larval CNS neuron                               |
 |__larval interneuron__________________________|
                                                larval Jaam3 neuron
                                                 |__larval abdominal 1 Jaam3 neuron
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Is a lineage NB5-2 primary interneuron
NB5-2 Notch OFF hemilineage primary neuron
larval interneuron
proprioceptive system neuron
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VFB:FBbt_00111658