FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term larval Saaghi 1 neuron ID (Ontology) FBbt:00111659 (Fly Anatomy)
Definition Larval GABAergic premotor neuron (Zarin et al., 2019) that is relatively late-born in the NB5-2 Notch ON primary hemilineage (Mark et al., 2021). Its primary neurite extends into the neuromere forming one arbor that extends anteriorly. One neurite crosses the midline and forms a terminal arbor that extends in a circular manner. It outputs to contralateral ventral and dorsal motorneurons. There is of these one neurons per hemisegment.[ FlyBase:FBrf0229965 FlyBase:FBrf0244727 FlyBase:FBrf0249021 ]
Also Known As "larval A06l neuron" ; "larval SA1 neuron"
Comment These neurons were identified in two EM reconstructions: one of the full CNS of a 6h old first instar larva, and another of abdominal segment 3 of a 12-24h old first instar larva. Only bilateral connections are reported. The number of identified input synapses in A1 was the following (number in brackets left/right): from A08e1 (2/3), from A08e2 (2/6), from A08e3 (4/5). The number of identified output synapses in A1 was the following (number in brackets left/right): to ventral motoneurons (33/15), to lateral motoneurons (2/8), to dorsal motoneurons (34/37). It is still not known if the pattern of connections is the same in the other abdominal segments (Heckscher et al., 2015).
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VFB:FBbt_00111659
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larval neuron
 |__larval premotor neuron_____________________
 |__larval GABAergic neuron____________________|
neuron                                         |
 |__abdominal neuron___________________________|
interneuron                                    |
 |__larval interneuron_________________________|
GABAergic neuron                               |
 |__larval GABAergic neuron____________________|
Notch ON hemilineage primary neuron            |
 |__NB5-2 Notch ON hemilineage primary neuron__|
NB5-2 lineage primary neuron                   |
 |__lineage NB5-2 primary interneuron__________|
 |__NB5-2 Notch ON hemilineage primary neuron__|
premotor neuron                                |
 |__larval premotor neuron_____________________|
primary interneuron                            |
 |__lineage NB5-2 primary interneuron__________|
larval CNS neuron                              |
 |__larval interneuron_________________________|
                                               larval Saaghi 1 neuron
                                                |__larval abdominal 1 Saaghi 1 neuron
                                                |__larval abdominal 2 Saaghi 1 neuron
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Is a lineage NB5-2 primary interneuron
abdominal neuron
NB5-2 Notch ON hemilineage primary neuron
larval premotor neuron
larval interneuron
larval GABAergic neuron
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VFB:FBbt_00111659