FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term larval A02a neuron ID (Ontology) FBbt:00111662 (Fly Anatomy)
Definition Larval period-positive median segmental interneuron (PMSI) (Kohsaka et al., 2019) that is late-born in the NB2-1 Notch OFF primary hemilineage (Mark et al., 2021). Like other PMSIs it has a ventral soma and it extends dorsally, close to the midline, then forms a loop in the dorsal neuropil (Kohsaka et al., 2019). This neuron additionally turns back ventrally, close to the midline, at the end of the loop (Schneider-Mizell et al., 2016; Kohsaka et al., 2019). It receives input from the ipsilateral dorsal bipolar neuron dbp and outputs to the ipsilateral A27j neuron and A02b neurons of both hemineuromeres (Schneider-Mizell et al., 2016).[ FlyBase:FBrf0231328 FlyBase:FBrf0242656 FlyBase:FBrf0249021 ]
Also Known As "looper-1"
Comment These neurons were identified in a EM reconstruction of a volume that includes the posterior half of abdominal segment 2 and abdominal segment 3, of a 12-24h old first instar larva. The number of connections was estimated from the publication figures. The number of input synapses was the following (number in brackets left/right; ipsi- and contralateral connections separated by comma): from dbp (35/35), A02b (5/10). The number of output synapses was the following: to A27j (15/10), A02b (8, 18/20, 18) (Schneider-Mizell et al., 2016). Looper-1 synonym from catmaid.
Links to External Ontologies
VFB:FBbt_00111662
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 larval A02a neuron (all annotations which use CV term, excluding "NOT" statements)       1      1
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lineage NB2-1 primary interneuron
 |__period-positive median segmental interneuron__
sensory system neuron                             |
 |__proprioceptive system neuron__________________|
Notch OFF hemilineage primary neuron              |
 |__NB2-1 Notch OFF hemilineage primary neuron____|
NB2-1 lineage primary neuron                      |
 |__NB2-1 Notch OFF hemilineage primary neuron____|
larval premotor neuron                            |
 |__period-positive median segmental interneuron__|
larval interneuron                                |
 |__period-positive median segmental interneuron__|
larval glutamatergic neuron                       |
 |__period-positive median segmental interneuron__|
                                                  larval A02a neuron  2 rec.
                                                   |__larval abdominal 1 A02a neuron
                                                   |__larval abdominal 3 A02a neuron
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Is a NB2-1 Notch OFF hemilineage primary neuron
proprioceptive system neuron
period-positive median segmental interneuron
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Synonyms
  • "looper-1" EXACT
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VFB:FBbt_00111662