FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term lobula plate-lobula columnar neuron LPLC2 ID (Ontology) FBbt:00111763 (Fly Anatomy)
Definition Lobula plate-lobula columnar neuron whose cell body lies in the dorsal area of the lateral cell body rind (Wu et al., 2016). It has a distinct dendritic arbor in each lobula plate layer, extending outwards from the main fiber in the direction of motion detection for the layer (Klapoetke et al., 2017). This arrangement allows it to detect looming (expansion) stimuli (Klapoetke et al., 2017). In the lobula, it has its main dendritic arbors in layers 4 and 5B, with minor processes in layer 5A, and presynaptic sites in layer 4 (Wu et al., 2016; Tanaka and Clark, 2022). Its arbors span approximately 25 lobula optic columns, overlapping with other LPLC2 cells (Wu et al., 2016). It projects to an optic glomerulus of the PVLP, anterior to LPLC1 and dorsal to LC4 (Wu et al., 2016). Its activity elicits a jump escape response (Wu et al., 2016; Klapoetke et al., 2017). There are approximately 80 of these cells per optic lobe (Wu et al., 2016) and they are cholinergic (Davis et al., 2020).[ FlyBase:FBrf0233032 FlyBase:FBrf0234700 FlyBase:FBrf0237184 FlyBase:FBrf0244935 FlyBase:FBrf0253297 ]
Also Known As "lobula complex columnar neuron LPLC2" ; "lobula plate and lobula columnar neuron 2" ; "LPL2CN" (for all, see Synonyms field below)
Comment Pre- versus postsynaptic innervation assessed with a presynaptic marker (synaptotagmin-HA driver) (Wu et al., 2016).
Links to External Ontologies
VFB:FBbt_00111763
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 lobula plate-lobula columnar neuron LPLC2 (all annotations which use CV term, excluding "NOT" statements)       2      2      9
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lobula complex columnar neuron
 |__lobula plate-lobula columnar neuron LPLC__
adult optic lobe columnar neuron              |
 |__optic lobe wide-field columnar neuron_____|
cholinergic neuron                            |
 |__adult cholinergic neuron__________________|
adult neuron                                  |
 |__adult cholinergic neuron__________________|
                                              lobula plate-lobula columnar neuron LPLC2  13 rec.
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Is a lobula plate-lobula columnar neuron LPLC
adult cholinergic neuron
optic lobe wide-field columnar neuron
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Synonyms
  • "lobula complex columnar neuron LPLC2" EXACT
    "lobula plate and lobula columnar neuron 2" EXACT
    "LPL2CN" EXACT[ FlyBase:FBrf0218239 ]
    "LPLC2" EXACT VFB_SYMBOL
Secondary IDs
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VFB:FBbt_00111763