FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term descending neuron of the posterior brain DNp52 ID (Ontology) FBbt:20001170 (Fly Anatomy)
Definition Adult descending neuron with its soma in the posterior brain, dorsal to the antler (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral flange, vest, crepine and lateral accessory lobe, and presynapses in the ipsilateral flange and vest (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).[ FlyBase:FBrf0246888 FlyBase:FBrf0259490 FlyBase:FBrf0260535 FlyBase:FBrf0260546 ]
Also Known As "adult crepine neuron 101" ; "CRE101" ; "DNp52"
Comment Cell type based on Hemibrain data (Scheffer et al., 2020) and updated using FlyWire (FAFB) data (Dorkenwald et al., 2024; Schlegel et al., 2024). CRE101 mapped to DNp52 by Schlegel et al. (2024) and DNp52 identified at light level by Sturner et al. (2024) - doi:10.1101/2024.06.04.596633. Soma location based on the closest annotated neuropil region. Pre- or post-synapse locations are the fewest regions that collectively contain at least 80 percent of all pre- or post-synapses of these neurons in FlyWire. Neurotransmitter predictions are from Eckstein et al. (2024). Other annotations are based on annotations in FlyWire and are available in the supplemental material of Schlegel et al. (2024).
Links to External Ontologies
VFB:FBbt_20001170
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neuron
 |__primary neuron____________________________
cholinergic neuron                            |
 |__adult cholinergic neuron__________________|
adult neuron                                  |
 |__adult cholinergic neuron__________________|
adult descending neuron                       |
 |__descending neuron of the posterior brain__|
CNS neuron                                    |
 |__supraesophageal ganglion neuron___________|
adult CNS neuron                              |
 |__descending neuron of the posterior brain__|
                                              descending neuron of the posterior brain DNp52
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Is a supraesophageal ganglion neuron
primary neuron
descending neuron of the posterior brain
adult cholinergic neuron
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VFB:FBbt_20001170